SNP Detail For rs2271293
1.Mapping Information
Human SNP ID rs2271293
Human chromosome chr16
Human SNP position 67868167
Pig chromosome chr6
Pig SNP position 25646236
2.Annotation Information
PubMed ID19060911
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/19060911
StudyLoci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.
Disease/TraitHDL cholesterol
Initial sample20,697 European ancestry individuals, 715 Orcadian individuals
Replication sampleNA
Region16q22.1
Chromosome idchr16
Chromosome position67868167
Reported geneCTCF, PRMT8
Mapped geneNUTF2
Upstream gene id
Downstream gene id
SNP gene ids10204
Upstream gene distance
Downstream gene distance
SNP risk allelers2271293-G
SNPsrs2271293
Merged0
SNP id current2271293
Contextintron_variant
Intergenic0
Allele frequency0.87
P value0.0000000000000008
Pvalue mlog15.096910013008
P value text
Or beta0.13
%95 Ci[NR] s.d. decrease
PlatformAffymetrix, Illumina [up to 600000]
CNVN
Mapped traithigh density lipoprotein cholesterol measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004612
Study accessionGCST000288
PubMed ID19060906
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/19060906
StudyCommon variants at 30 loci contribute to polygenic dyslipidemia.
Disease/TraitHDL cholesterol
Initial sample19,840 European ancestry individuals
Replication sampleUp to 20,623 European ancestry individuals
Region16q22.1
Chromosome idchr16
Chromosome position67868167
Reported geneLCAT
Mapped geneNUTF2
Upstream gene id
Downstream gene id
SNP gene ids10204
Upstream gene distance
Downstream gene distance
SNP risk allelers2271293-A
SNPsrs2271293
Merged0
SNP id current2271293
Contextintron_variant
Intergenic0
Allele frequency0.11
P value0.0000000000009
Pvalue mlog12.0457574905606
P value text
Or beta0.07
%95 Ci[0.01-0.13] s.d. increase
PlatformAffymetrix, Illumina [~ 2600000] (imputed)
CNVN
Mapped traithigh density lipoprotein cholesterol measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004612
Study accessionGCST000290