SNP Detail For rs2270875
1.Mapping Information
Human SNP ID rs2270875
Human chromosome chr8
Human SNP position 131987689
Pig chromosome chr4
Pig SNP position 9124412
2.Annotation Information
PubMed ID23374588
JournalNeurobiol Aging
Linkwww.ncbi.nlm.nih.gov/pubmed/23374588
StudyPharmacogenomics in Alzheimer__s disease: a genome-wide association study of response to cholinesterase inhibitors.
Disease/TraitResponse to cholinesterase inhibitors in Alzheimer__s disease
Initial sample92 European ancestry cases, 77 European ancestry controls
Replication sample94 European ancestry cases, 74 European ancestry controls
Region8q24.22
Chromosome idchr8
Chromosome position131987689
Reported geneEFR3A
Mapped geneEFR3A
Upstream gene id
Downstream gene id
SNP gene ids23167
Upstream gene distance
Downstream gene distance
SNP risk allelers2270875-G
SNPsrs2270875
Merged0
SNP id current2270875
Contextsynonymous_variant
Intergenic0
Allele frequency0.16
P value0.000009
Pvalue mlog5.04575749056067
P value text(MMSE)
Or beta2.84
%95 Ci[NR] unit decrease
PlatformIllumina [522109]
CNVN
Mapped traitresponse to cholinesterase inhibitor, Alzheimers disease
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005195, http://www.ebi.ac.uk/efo/EFO_0000249
Study accessionGCST001835