Human SNP ID | rs2270875 |
---|---|
Human chromosome | chr8 |
Human SNP position | 131987689 |
Pig chromosome | chr4 |
Pig SNP position | 9124412 |
PubMed ID | 23374588 |
---|---|
Journal | Neurobiol Aging |
Link | www.ncbi.nlm.nih.gov/pubmed/23374588 |
Study | Pharmacogenomics in Alzheimer__s disease: a genome-wide association study of response to cholinesterase inhibitors. |
Disease/Trait | Response to cholinesterase inhibitors in Alzheimer__s disease |
Initial sample | 92 European ancestry cases, 77 European ancestry controls |
Replication sample | 94 European ancestry cases, 74 European ancestry controls |
Region | 8q24.22 |
Chromosome id | chr8 |
Chromosome position | 131987689 |
Reported gene | EFR3A |
Mapped gene | EFR3A |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 23167 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2270875-G |
SNPs | rs2270875 |
Merged | 0 |
SNP id current | 2270875 |
Context | synonymous_variant |
Intergenic | 0 |
Allele frequency | 0.16 |
P value | 0.000009 |
Pvalue mlog | 5.04575749056067 |
P value text | (MMSE) |
Or beta | 2.84 |
%95 Ci | [NR] unit decrease |
Platform | Illumina [522109] |
CNV | N |
Mapped trait | response to cholinesterase inhibitor, Alzheimers disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005195, http://www.ebi.ac.uk/efo/EFO_0000249 |
Study accession | GCST001835 |