Human SNP ID | rs2270450 |
---|---|
Human chromosome | chr6 |
Human SNP position | 46677138 |
Pig chromosome | chr7 |
Pig SNP position | 48120011 |
PubMed ID | 25429627 |
---|---|
Journal | J Clin Endocrinol Metab |
Link | www.ncbi.nlm.nih.gov/pubmed/25429627 |
Study | Identification of a Hashimoto thyroiditis susceptibility locus via a genome-wide comparison with Graves__ disease. |
Disease/Trait | Hashimoto thyroiditis versus Graves__ disease |
Initial sample | 263 Japanese ancestry Hashimoto thyroiditis cases, 260 Japanese ancestry Graves鈥?disease cases |
Replication sample | 181 Japanese ancestry Hashimoto thyroiditis cases, 286 Japanese ancestry Graves鈥?disease cases |
Region | 6p12.3 |
Chromosome id | chr6 |
Chromosome position | 46677138 |
Reported gene | SLC25A27 |
Mapped gene | LOC101926934, SLC25A27 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 101926934, 9481 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2270450-T |
SNPs | rs2270450 |
Merged | 0 |
SNP id current | 2270450 |
Context | 3_prime_UTR_variant |
Intergenic | 0 |
Allele frequency | 0.178 |
P value | 0.000001 |
Pvalue mlog | 6 |
P value text | |
Or beta | 1.75 |
%95 Ci | [1.40-2.19] |
Platform | Illumina [546173] |
CNV | N |
Mapped trait | autoimmune thyroid disease, Hashimoto__s thyroiditis, Graves disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0006812, http://www.ebi.ac.uk/efo/EFO_0003779, http://www.ebi.ac.uk/efo/EFO_0004237 |
Study accession | GCST002705 |