Human SNP ID | rs2259816 |
---|---|
Human chromosome | chr12 |
Human SNP position | 120997784 |
Pig chromosome | chr14 |
Pig SNP position | 43397758 |
PubMed ID | 19198612 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/19198612 |
Study | New susceptibility locus for coronary artery disease on chromosome 3q22.3. |
Disease/Trait | Coronary heart disease |
Initial sample | 1,222 European ancestry cases, 1,298 European ancestry controls |
Replication sample | 18,185 European ancestry cases, 20,068 European ancestry controls |
Region | 12q24.31 |
Chromosome id | chr12 |
Chromosome position | 120997784 |
Reported gene | C12orf43, HNF1A |
Mapped gene | HNF1A |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 6927 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2259816-T |
SNPs | rs2259816 |
Merged | 0 |
SNP id current | 2259816 |
Context | synonymous_variant |
Intergenic | 0 |
Allele frequency | 0.36 |
P value | 0.0000005 |
Pvalue mlog | 6.30102999566398 |
P value text | |
Or beta | 1.08 |
%95 Ci | [1.05-1.11] |
Platform | Affymetrix [567119] |
CNV | N |
Mapped trait | coronary heart disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0001645 |
Study accession | GCST000338 |
PubMed ID | 22939635 |
Journal | Am J Hum Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/22939635 |
Study | Genome-wide association and population genetic analysis of C-reactive protein in African American and Hispanic American women. |
Disease/Trait | C-reactive protein |
Initial sample | 8,280 African American female individuals, 3,548 Hispanic female individuals |
Replication sample | 3,787 African American female individuals, 3,548 Hispanic female individuals, 5,656 European ancestry individuals |
Region | 12q24.31 |
Chromosome id | chr12 |
Chromosome position | 120997784 |
Reported gene | OASL, C12orf43, HNF1A |
Mapped gene | HNF1A |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 6927 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2259816-T |
SNPs | rs2259816 |
Merged | 0 |
SNP id current | 2259816 |
Context | synonymous_variant |
Intergenic | 0 |
Allele frequency | 0.379 |
P value | 0.0000000003 |
Pvalue mlog | 9.52287874528033 |
P value text | (HA women) |
Or beta | 0.141 |
%95 Ci | [0.092-0.190] unit increase |
Platform | Affymetrix [up to 2203609] (imputed) |
CNV | N |
Mapped trait | C-reactive protein measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004458 |
Study accession | GCST001650 |