SNP Detail For rs2256609
1.Mapping Information
Human SNP ID rs2256609
Human chromosome chr22
Human SNP position 21570728
Pig chromosome chr14
Pig SNP position 53763163
2.Annotation Information
PubMed ID26192919
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26192919
StudyAssociation analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.
Disease/TraitCrohn__s disease
Initial sample5,956 European ancestry cases, 14,927 European ancestry controls
Replication sample14,594 European ancestry cases, 26,715 European ancestry controls, 151 Iranian ancestry cases, 342 Iranian ancestry controls, 184 Indian ancestry cases, 990 Indian ancestry controls, 1,690 East Asian ancestry cases, 3,719 East Asian ancestry controls
Region22q11.21
Chromosome idchr22
Chromosome position21570728
Reported geneNR
Mapped geneUBE2L3
Upstream gene id
Downstream gene id
SNP gene ids7332
Upstream gene distance
Downstream gene distance
SNP risk allelers2256609-G
SNPsrs2256609
Merged
SNP id current2256609
Contextintron_variant
Intergenic0
Allele frequency0.1971
P value0.000000000006
Pvalue mlog11.2218487496163
P value text(EA)
Or beta1.1082332
%95 Ci[1.08-1.14]
PlatformAffymetrix, Illumina [~ 9000000] (imputed)
CNVN
Mapped traitCrohn__s disease
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000384
Study accessionGCST003044