SNP Detail For rs2240466
1.Mapping Information
Human SNP ID rs2240466
Human chromosome chr7
Human SNP position 73441939
Pig chromosome chr3
Pig SNP position 10462283
2.Annotation Information
PubMed ID19060911
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/19060911
StudyLoci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.
Disease/TraitTriglycerides
Initial sample17,100 European ancestry individuals, 715 Orcadian individuals
Replication sampleNA
Region7q11.23
Chromosome idchr7
Chromosome position73441939
Reported geneMLXIPL
Mapped geneBAZ1B
Upstream gene id
Downstream gene id
SNP gene ids9031
Upstream gene distance
Downstream gene distance
SNP risk allelers2240466-G
SNPsrs2240466
Merged0
SNP id current2240466
Context3_prime_UTR_variant
Intergenic0
Allele frequency0.87
P value0.000000000001
Pvalue mlog12
P value text
Or beta0.14
%95 Ci[NR] s.d. increase
PlatformAffymetrix, Illumina [up to 600000]
CNVN
Mapped traittriglyceride measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004530
Study accessionGCST000289
PubMed ID21490707
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/21490707
StudyGenome-wide meta-analysis identifies regions on 7p21 (AHR) and 15q24 (CYP1A2) as determinants of habitual caffeine consumption.
Disease/TraitCaffeine consumption
Initial sample47,431 European ancestry individuals
Replication sampleNA
Region7q11.23
Chromosome idchr7
Chromosome position73441939
Reported geneNR
Mapped geneBAZ1B
Upstream gene id
Downstream gene id
SNP gene ids9031
Upstream gene distance
Downstream gene distance
SNP risk allelers2240466-A
SNPsrs2240466
Merged0
SNP id current2240466
Context3_prime_UTR_variant
Intergenic0
Allele frequency0.12
P value0.000001
Pvalue mlog6
P value text
Or beta0.1109
%95 Ci[0.07-0.15] mg/day increase
PlatformAffymetrix, Illumina [~ 2500000] (imputed)
CNVN
Mapped traitcoffee consumption
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004330
Study accessionGCST001032