Human SNP ID | rs2233434 |
---|---|
Human chromosome | chr6 |
Human SNP position | 44265183 |
Pig chromosome | chr7 |
Pig SNP position | 45132408 |
PubMed ID | 22446963 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/22446963 |
Study | Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population. |
Disease/Trait | Rheumatoid arthritis |
Initial sample | 4,074 Japanese ancestry cases, 16,891 Japanese ancestry controls |
Replication sample | 5,277 Japanese ancestry cases, 21,684 Japanese ancestry controls |
Region | 6p21.1 |
Chromosome id | chr6 |
Chromosome position | 44265183 |
Reported gene | NFKBIE |
Mapped gene | NFKBIE |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 4794 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2233434-G |
SNPs | rs2233434 |
Merged | 0 |
SNP id current | 2233434 |
Context | missense_variant |
Intergenic | 0 |
Allele frequency | 0.21 |
P value | 6E-19 |
Pvalue mlog | 18.2218487496163 |
P value text | |
Or beta | 1.19 |
%95 Ci | [1.15-1.24] |
Platform | Affymetrix, Illumina [1948139] |
CNV | N |
Mapped trait | rheumatoid arthritis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000685 |
Study accession | GCST001454 |
PubMed ID | 23028356 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23028356 |
Study | Functional variants in NFKBIE and RTKN2 involved in activation of the NF-κB pathway are associated with rheumatoid arthritis in Japanese. |
Disease/Trait | Rheumatoid arthritis |
Initial sample | 2,303 Japanese ancestry cases, 3,380 Japanese ancestry controls |
Replication sample | 5,604 Japanese ancestry cases, 31,982 Japanese ancestry controls |
Region | 6p21.1 |
Chromosome id | chr6 |
Chromosome position | 44265183 |
Reported gene | NFKBIE |
Mapped gene | NFKBIE |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 4794 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2233434-G |
SNPs | rs2233434 |
Merged | 0 |
SNP id current | 2233434 |
Context | missense_variant |
Intergenic | 0 |
Allele frequency | 0.215 |
P value | 0.000000000000001 |
Pvalue mlog | 15 |
P value text | |
Or beta | 1.2 |
%95 Ci | [1.15-1.26] |
Platform | Illumina [NR] |
CNV | N |
Mapped trait | rheumatoid arthritis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000685 |
Study accession | GCST001681 |