SNP Detail For rs2229288
1.Mapping Information
Human SNP ID rs2229288
Human chromosome chr16
Human SNP position 72794405
Pig chromosome chr6
Pig SNP position 15067169
2.Annotation Information
PubMed ID26265699
JournalBlood
Linkwww.ncbi.nlm.nih.gov/pubmed/26265699
StudyGenetics of glucocorticoid-associated osteonecrosis in children with acute lymphoblastic leukemia.
Disease/TraitGlucocorticoid-induced osteonecrosis
Initial sample274 European ancestry osteonecrosis cases, 25 Black osteonecrosis cases, 68 Hispanic osteonecrosis cases, 6 Asian ancestry osteonecrosis cases, 27 other ancestry osteonecrosis cases, 1,477 European ancestry treated controls, 223 Black treated controls, 5
Replication sampleNA
Region16q22.2
Chromosome idchr16
Chromosome position72794405
Reported geneZFHX3
Mapped geneLOC105371339, ZFHX3
Upstream gene id
Downstream gene id
SNP gene ids105371339, 463
Upstream gene distance
Downstream gene distance
SNP risk allelers2229288-C
SNPsrs2229288
Merged
SNP id current2229288
Contextmissense_variant
Intergenic0
Allele frequency0.0022
P value0.000001
Pvalue mlog6
P value text
Or beta
%95 Ci
PlatformAffymetrix, Illumina [NR] (imputed)
CNVN
Mapped traitresponse to glucocorticoid, osteonecrosis
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0051384, http://www.ebi.ac.uk/efo/EFO_0004259
Study accessionGCST003084