SNP Detail For rs2228467
1.Mapping Information
Human SNP ID rs2228467
Human chromosome chr3
Human SNP position 42864624
Pig chromosome chr13
Pig SNP position 28991518
2.Annotation Information
PubMed ID23314186
JournalHum Mol Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23314186
StudyGenetic variation associated with circulating monocyte count in the eMERGE Network.
Disease/TraitMonocyte count
Initial sample9,849 European ancestry individuals, 894 African ancestry individuals, 271 individuals
Replication sampleNA
Region3p22.1
Chromosome idchr3
Chromosome position42864624
Reported geneCCBP2
Mapped geneACKR2
Upstream gene id
Downstream gene id
SNP gene ids1238
Upstream gene distance
Downstream gene distance
SNP risk allelers2228467-G
SNPsrs2228467
Merged0
SNP id current2228467
Contextmissense_variant
Intergenic0
Allele frequency0.06
P value0.0000002
Pvalue mlog6.69897000433601
P value text
Or beta0.3
%95 Ciunit increase
PlatformIllumina [NR]
CNVN
Mapped traitmonocyte count
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005091
Study accessionGCST001887
PubMed ID25340798
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/25340798
StudyGenome-Wide Association Study of CSF Levels of 59 Alzheimer__s Disease Candidate Proteins: Significant Associations with Proteins Involved in Amyloid Processing and Inflammation.
Disease/TraitCerebrospinal fluid levels of Alzheimer__s disease-related proteins
Initial sample574 individuals
Replication sampleNA
Region3p22.1
Chromosome idchr3
Chromosome position42864624
Reported geneCCBP2
Mapped geneACKR2
Upstream gene id
Downstream gene id
SNP gene ids1238
Upstream gene distance
Downstream gene distance
SNP risk allelers2228467-G
SNPsrs2228467
Merged0
SNP id current2228467
Contextmissense_variant
Intergenic0
Allele frequencyNR
P value0.000000000000000004
Pvalue mlog17.397940008672
P value text(Monocyte chemotactic protein 1)
Or beta
%95 Ci
PlatformIllumina [5815690] (imputed)
CNVN
Mapped traitAlzheimers disease, Alzheimer__s disease biomarker measurement, CCL2 measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000249, http://www.ebi.ac.uk/efo/EFO_0006514, http://www.ebi.ac.uk/efo/EFO_0004749
Study accessionGCST002665