SNP Detail For rs2164983
1.Mapping Information
Human SNP ID rs2164983
Human chromosome chr19
Human SNP position 8679120
Pig chromosome chr2
Pig SNP position 71006616
2.Annotation Information
PubMed ID22197932
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/22197932
StudyMeta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis.
Disease/TraitAtopic dermatitis
Initial sample5,606 European ancestry cases, 20,565 European ancestry controls
Replication sample5,419 European ancestry cases, 19,833 European ancestry controls
Region19p13.2
Chromosome idchr19
Chromosome position8679120
Reported geneACTL9
Mapped geneLOC105372267 - ACTL9
Upstream gene id105372267
Downstream gene id284382
SNP gene ids
Upstream gene distance1127
Downstream gene distance18277
SNP risk allelers2164983-A
SNPsrs2164983
Merged0
SNP id current2164983
Contextdownstream_gene_variant
Intergenic1
Allele frequency0.15
P value0.000000007
Pvalue mlog8.15490195998574
P value text
Or beta1.16
%95 Ci[1.10-1.22]
PlatformAffymetrix, Illumina [~ 2500000] (imputed)
CNVN
Mapped traitatopic eczema
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000274
Study accessionGCST001363
PubMed ID26482879
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26482879
StudyMulti-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis.
Disease/TraitAtopic dermatitis
Initial sample18,900 European ancestry cases, 1,472 Japanese ancestry cases, 422 African American cases, 300 Latino cases, 305 cases, 84,166 European ancestry controls, 7,966 Japanese ancestry controls, 844 African American controls, 1,592 Latino controls, 896 controls
Replication sample30,588 European ancestry cases, 459 African American cases, 1,012 Chinese ancestry cases, 226,537 European ancestry controls, 729 African American controls, 1,362 Chinese ancestry controls
Region19p13.2
Chromosome idchr19
Chromosome position8679120
Reported geneACTL9
Mapped geneLOC105372267 - ACTL9
Upstream gene id105372267
Downstream gene id284382
SNP gene ids
Upstream gene distance1127
Downstream gene distance18277
SNP risk allelers2164983-A
SNPsrs2164983
Merged0
SNP id current2164983
Contextdownstream_gene_variant
Intergenic1
Allele frequencyNR
P value0.00000000002
Pvalue mlog10.698970004336
P value text(EA, fixed effects)
Or beta1.12
%95 Ci[1.08-1.15]
PlatformIllumina [15539996] (imputed)
CNVN
Mapped traitatopic eczema
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000274
Study accessionGCST003184