SNP Detail For rs216172
1.Mapping Information
Human SNP ID rs216172
Human chromosome chr17
Human SNP position 2223210
Pig chromosome chr12
Pig SNP position 50174381
2.Annotation Information
PubMed ID21378990
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/21378990
StudyLarge-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.
Disease/TraitCoronary heart disease
Initial sample22,233 European ancestry cases, 64,762 European ancestry controls
Replication sample56,682 European ancestry cases and controls
Region17p13.3
Chromosome idchr17
Chromosome position2223210
Reported geneSMG6, SRR
Mapped geneSMG6
Upstream gene id
Downstream gene id
SNP gene ids23293
Upstream gene distance
Downstream gene distance
SNP risk allelers216172-C
SNPsrs216172
Merged0
SNP id current216172
Contextintron_variant
Intergenic0
Allele frequency0.37
P value0.000000001
Pvalue mlog9
P value text
Or beta1.07
%95 Ci[1.05-1.09]
PlatformAffymetrix, Illumina [~ 2300000] (imputed)
CNVN
Mapped traitcoronary heart disease
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001645
Study accessionGCST000998
PubMed ID26343387
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26343387
StudyA comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease.
Disease/TraitCoronary artery disease
Initial sample42,096 European ancestry cases, 361 African American cases, 758 Hispanic American cases, 12,658 South Asian ancestry cases, 1,802 Lebanese ancestry cases, 3,614 East Asian ancestry cases, 99,121 European ancestry controls, 2,778 African American controls,
Replication sampleNA
Region17p13.3
Chromosome idchr17
Chromosome position2223210
Reported geneSMG6
Mapped geneSMG6
Upstream gene id
Downstream gene id
SNP gene ids23293
Upstream gene distance
Downstream gene distance
SNP risk allelers216172-C
SNPsrs216172
Merged0
SNP id current216172
Contextintron_variant
Intergenic0
Allele frequency0.349997
P value0.0000005
Pvalue mlog6.30102999566398
P value text
Or beta1.05
%95 Ci[1.03- 1.07]
PlatformAffymetrix, Illumina [8600000] (imputed)
CNVN
Mapped traitcoronary artery disease
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000378
Study accessionGCST003116