SNP Detail For rs2154490
1.Mapping Information
Human SNP ID rs2154490
Human chromosome chr21
Human SNP position 29543641
Pig chromosome chr13
Pig SNP position 203419589
2.Annotation Information
PubMed ID26265699
JournalBlood
Linkwww.ncbi.nlm.nih.gov/pubmed/26265699
StudyGenetics of glucocorticoid-associated osteonecrosis in children with acute lymphoblastic leukemia.
Disease/TraitGlucocorticoid-induced osteonecrosis
Initial sample274 European ancestry osteonecrosis cases, 25 Black osteonecrosis cases, 68 Hispanic osteonecrosis cases, 6 Asian ancestry osteonecrosis cases, 27 other ancestry osteonecrosis cases, 1,477 European ancestry treated controls, 223 Black treated controls, 5
Replication sampleNA
Region21q21.3
Chromosome idchr21
Chromosome position29543641
Reported geneGRIK1
Mapped geneGRIK1
Upstream gene id
Downstream gene id
SNP gene ids2897
Upstream gene distance
Downstream gene distance
SNP risk allelers2154490-A
SNPsrs2154490
Merged
SNP id current2154490
Contextintron_variant
Intergenic0
Allele frequency0.222
P value0.000001
Pvalue mlog6
P value text
Or beta
%95 Ci
PlatformAffymetrix, Illumina [NR] (imputed)
CNVN
Mapped traitresponse to glucocorticoid, osteonecrosis
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0051384, http://www.ebi.ac.uk/efo/EFO_0004259
Study accessionGCST003084