Human SNP ID | rs2131925 |
---|---|
Human chromosome | chr1 |
Human SNP position | 62560271 |
Pig chromosome | chr6 |
Pig SNP position | 138141064 |
PubMed ID | 20686565 |
---|---|
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/20686565 |
Study | Biological, clinical and population relevance of 95 loci for blood lipids. |
Disease/Trait | LDL cholesterol |
Initial sample | 95,454 European ancestry individuals |
Replication sample | NA |
Region | 1p31.3 |
Chromosome id | chr1 |
Chromosome position | 62560271 |
Reported gene | DOCK7, ANGPTL3 |
Mapped gene | DOCK7 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 85440 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2131925-G |
SNPs | rs2131925 |
Merged | 0 |
SNP id current | 2131925 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.32 |
P value | 0.000000000000000003 |
Pvalue mlog | 17.5228787452803 |
P value text | |
Or beta | 1.59 |
%95 Ci | [1.22-1.96] mg/dL decrease |
Platform | Affymetrix, Illumina, Perlegen [~ 2600000] (imputed) |
CNV | N |
Mapped trait | low density lipoprotein cholesterol measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004611 |
Study accession | GCST000759 |
PubMed ID | 20686565 |
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/20686565 |
Study | Biological, clinical and population relevance of 95 loci for blood lipids. |
Disease/Trait | Triglycerides |
Initial sample | 96,598 European ancestry individuals |
Replication sample | NA |
Region | 1p31.3 |
Chromosome id | chr1 |
Chromosome position | 62560271 |
Reported gene | DOCK7, ANGPTL3 |
Mapped gene | DOCK7 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 85440 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2131925-G |
SNPs | rs2131925 |
Merged | 0 |
SNP id current | 2131925 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.32 |
P value | 9E-43 |
Pvalue mlog | 42.0457574905606 |
P value text | |
Or beta | 4.94 |
%95 Ci | [4.16-5.72] mg/dL decrease |
Platform | Affymetrix, Illumina, Perlegen [~ 2600000] (imputed) |
CNV | N |
Mapped trait | triglyceride measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004530 |
Study accession | GCST000758 |
PubMed ID | 20686565 |
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/20686565 |
Study | Biological, clinical and population relevance of 95 loci for blood lipids. |
Disease/Trait | Cholesterol, total |
Initial sample | 100,184 European ancestry individuals |
Replication sample | NA |
Region | 1p31.3 |
Chromosome id | chr1 |
Chromosome position | 62560271 |
Reported gene | DOCK7, ANGPTL3 |
Mapped gene | DOCK7 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 85440 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2131925-G |
SNPs | rs2131925 |
Merged | 0 |
SNP id current | 2131925 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.32 |
P value | 5E-41 |
Pvalue mlog | 40.3010299956639 |
P value text | |
Or beta | 2.6 |
%95 Ci | [2.21-2.99] mg/dL decrease |
Platform | Affymetrix, Illumina, Perlegen [~ 2600000] (imputed) |
CNV | N |
Mapped trait | total cholesterol measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004574 |
Study accession | GCST000760 |
PubMed ID | 24097068 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24097068 |
Study | Discovery and refinement of loci associated with lipid levels. |
Disease/Trait | LDL cholesterol |
Initial sample | 94,595 European ancestry individuals |
Replication sample | 93,982 European ancestry individuals |
Region | 1p31.3 |
Chromosome id | chr1 |
Chromosome position | 62560271 |
Reported gene | ANGPTL3 |
Mapped gene | DOCK7 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 85440 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2131925-G |
SNPs | rs2131925 |
Merged | 0 |
SNP id current | 2131925 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.34 |
P value | 3E-32 |
Pvalue mlog | 31.5228787452803 |
P value text | |
Or beta | 0.049 |
%95 Ci | [NR] unit decrease |
Platform | NR [NR] (imputed) |
CNV | N |
Mapped trait | low density lipoprotein cholesterol measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004611 |
Study accession | GCST002222 |
PubMed ID | 24097068 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24097068 |
Study | Discovery and refinement of loci associated with lipid levels. |
Disease/Trait | Cholesterol, total |
Initial sample | 94,595 European ancestry individuals |
Replication sample | 93,982 European ancestry individuals |
Region | 1p31.3 |
Chromosome id | chr1 |
Chromosome position | 62560271 |
Reported gene | ANGPTL3 |
Mapped gene | DOCK7 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 85440 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2131925-G |
SNPs | rs2131925 |
Merged | 0 |
SNP id current | 2131925 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.34 |
P value | 4E-80 |
Pvalue mlog | 79.397940008672 |
P value text | |
Or beta | 0.075 |
%95 Ci | [NR] unit decrease |
Platform | NR [NR] (imputed) |
CNV | N |
Mapped trait | total cholesterol measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004574 |
Study accession | GCST002221 |
PubMed ID | 24097068 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24097068 |
Study | Discovery and refinement of loci associated with lipid levels. |
Disease/Trait | Triglycerides |
Initial sample | 94,595 European ancestry individuals |
Replication sample | 93,982 European ancestry individuals |
Region | 1p31.3 |
Chromosome id | chr1 |
Chromosome position | 62560271 |
Reported gene | ANGPTL3 |
Mapped gene | DOCK7 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 85440 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2131925-G |
SNPs | rs2131925 |
Merged | 0 |
SNP id current | 2131925 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.34 |
P value | 3E-74 |
Pvalue mlog | 73.5228787452803 |
P value text | |
Or beta | 0.066 |
%95 Ci | [NR] mg/dL decrease |
Platform | NR [NR] (imputed) |
CNV | N |
Mapped trait | triglyceride measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004530 |
Study accession | GCST002216 |