SNP Detail For rs2126200
1.Mapping Information
Human SNP ID rs2126200
Human chromosome chr11
Human SNP position 123002368
Pig chromosome chr9
Pig SNP position 55276295
2.Annotation Information
PubMed ID23382691
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23382691
StudyLoci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Disease/TraitIgG glycosylation
Initial sample2,247 European ancestry individuals
Replication sampleNA
Region11q24.1
Chromosome idchr11
Chromosome position123002368
Reported geneNR
Mapped geneBSX - LOC341056
Upstream gene id390259
Downstream gene id341056
SNP gene ids
Upstream gene distance20697
Downstream gene distance15198
SNP risk allelers2126200-C
SNPsrs2126200
Merged0
SNP id current2126200
Contextintergenic_variant
Intergenic1
Allele frequency0.541753456007146
P value0.000007
Pvalue mlog5.15490195998574
P value text(IGP21)
Or beta0.1392
%95 Ci[0.078-0.2] unit decrease
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitserum IgG glycosylation measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005193
Study accessionGCST001848