SNP Detail For rs2090104
1.Mapping Information
Human SNP ID rs2090104
Human chromosome chr4
Human SNP position 127545545
Pig chromosome chr8
Pig SNP position 104230665
2.Annotation Information
PubMed ID23382691
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23382691
StudyLoci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Disease/TraitIgG glycosylation
Initial sample2,247 European ancestry individuals
Replication sampleNA
Region4q28.1
Chromosome idchr4
Chromosome position127545545
Reported geneNR
Mapped geneLOC101060158 - LOC105377412
Upstream gene id101060158
Downstream gene id105377412
SNP gene ids
Upstream gene distance46724
Downstream gene distance19518
SNP risk allelers2090104-G
SNPsrs2090104
Merged0
SNP id current2090104
Contextintergenic_variant
Intergenic1
Allele frequency0.335522302949062
P value0.000005
Pvalue mlog5.30102999566398
P value text(IGP74)
Or beta0.1533
%95 Ci[0.087-0.219] unit decrease
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitserum IgG glycosylation measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005193
Study accessionGCST001848