SNP Detail For rs2082412
1.Mapping Information
Human SNP ID rs2082412
Human chromosome chr5
Human SNP position 159290781
Pig chromosome chr16
Pig SNP position 70031381
2.Annotation Information
PubMed ID19169254
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/19169254
StudyGenome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways.
Disease/TraitPsoriasis
Initial sample1,359 European ancestry cases, 1,400 European ancestry controls
Replication sample5,048 European ancestry cases, 5,041 European ancestry controls
Region5q33.3
Chromosome idchr5
Chromosome position159290781
Reported geneIL12B
Mapped geneUBLCP1 - LOC105377683
Upstream gene id134510
Downstream gene id105377683
SNP gene ids
Upstream gene distance4741
Downstream gene distance20011
SNP risk allelers2082412-G
SNPsrs2082412
Merged0
SNP id current2082412
Contextdownstream_gene_variant
Intergenic1
Allele frequency0.8
P value2E-28
Pvalue mlog27.698970004336
P value text
Or beta1.44
%95 Ci[NR]
PlatformPerlegen [~ 2500000] (imputed)
CNVN
Mapped traitpsoriasis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000676
Study accessionGCST000322
PubMed ID26626624
JournalAm J Hum Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26626624
StudyGenome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture.
Disease/TraitCutaneous psoriasis
Initial sample1,363 European ancestry cases, 4,934 European ancestry controls
Replication sampleup to 2,969 European ancestry cases, up to European ancestry 14,384 controls
Region5q33.3
Chromosome idchr5
Chromosome position159290781
Reported geneIL12B
Mapped geneUBLCP1 - LOC105377683
Upstream gene id134510
Downstream gene id105377683
SNP gene ids
Upstream gene distance4741
Downstream gene distance20011
SNP risk allelers2082412-G
SNPsrs2082412
Merged0
SNP id current2082412
Contextdownstream_gene_variant
Intergenic1
Allele frequencyNR
P value0.0000000000001
Pvalue mlog13
P value text
Or beta1.35
%95 CiNR
PlatformIllumina [11532644] (imputed)
CNVN
Mapped traitpsoriasis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000676
Study accessionGCST003269