SNP Detail For rs2075876
1.Mapping Information
Human SNP ID rs2075876
Human chromosome chr21
Human SNP position 44289270
Pig chromosome chr13
Pig SNP position 217030889
2.Annotation Information
PubMed ID21505073
JournalHum Mol Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/21505073
StudyThe human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population.
Disease/TraitRheumatoid arthritis
Initial sample1,247 Japanese ancestry cases, 1,486 Japanese ancestry controls
Replication sample4,168 Japanese ancestry cases, 5,003 Japanese ancestry controls
Region21q22.3
Chromosome idchr21
Chromosome position44289270
Reported geneAIRE, PFKL
Mapped geneAIRE
Upstream gene id
Downstream gene id
SNP gene ids326
Upstream gene distance
Downstream gene distance
SNP risk allelers2075876-A
SNPsrs2075876
Merged0
SNP id current2075876
Contextnon_coding_transcript_exon_variant
Intergenic0
Allele frequency0.34
P value0.000000004
Pvalue mlog8.39794000867203
P value text
Or beta1.18
%95 Ci[1.11-1.24]
PlatformIllumina [241523]
CNVN
Mapped traitrheumatoid arthritis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000685
Study accessionGCST001042