SNP Detail For rs2074409
1.Mapping Information
Human SNP ID rs2074409
Human chromosome chr17
Human SNP position 37538240
Pig chromosome chr12
Pig SNP position 40638313
2.Annotation Information
PubMed ID22566498
JournalHypertension
Linkwww.ncbi.nlm.nih.gov/pubmed/22566498
StudyGenomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker.
Disease/TraitResponse to angiotensin II receptor blocker therapy
Initial sample198 European ancestry hypertensive individuals, 193 African American hypertensive individuals
Replication sampleNA
Region17q12
Chromosome idchr17
Chromosome position37538240
Reported geneSYNRG
Mapped geneSYNRG
Upstream gene id
Downstream gene id
SNP gene ids11276
Upstream gene distance
Downstream gene distance
SNP risk allelers2074409-T
SNPsrs2074409
Merged0
SNP id current2074409
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.000002
Pvalue mlog5.69897000433601
P value text(EA)
Or beta1.2
%95 Ci[0.67-1.73] unit increase
PlatformAffymetrix [~ 2300000] (imputed)
CNVN
Mapped traitresponse to candesartan, hypertension
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_1901556, http://www.ebi.ac.uk/efo/EFO_0000537
Study accessionGCST001520