Human SNP ID | rs2072209 |
---|---|
Human chromosome | chr7 |
Human SNP position | 107951753 |
Pig chromosome | chr9 |
Pig SNP position | 118466583 |
PubMed ID | 23382691 |
---|---|
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 7q31.1 |
Chromosome id | chr7 |
Chromosome position | 107951753 |
Reported gene | LAMB1 |
Mapped gene | LAMB1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3912 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2072209-G |
SNPs | rs2072209 |
Merged | 0 |
SNP id current | 2072209 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.0582759206419973 |
P value | 0.00000001 |
Pvalue mlog | 8 |
P value text | (IGP69) |
Or beta | 0.3742 |
%95 Ci | [0.25-0.5] unit decrease |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |
PubMed ID | 23382691 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 7q31.1 |
Chromosome id | chr7 |
Chromosome position | 107951753 |
Reported gene | LAMB1 |
Mapped gene | LAMB1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3912 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2072209-G |
SNPs | rs2072209 |
Merged | 0 |
SNP id current | 2072209 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.0584063163538874 |
P value | 0.000002 |
Pvalue mlog | 5.69897000433601 |
P value text | (IGP74) |
Or beta | 0.3125 |
%95 Ci | [0.18-0.44] unit decrease |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |
PubMed ID | 23382691 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 7q31.1 |
Chromosome id | chr7 |
Chromosome position | 107951753 |
Reported gene | LAMB1 |
Mapped gene | LAMB1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3912 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2072209-G |
SNPs | rs2072209 |
Merged | 0 |
SNP id current | 2072209 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.0582759937583593 |
P value | 0.0000002 |
Pvalue mlog | 6.69897000433601 |
P value text | (IGP75) |
Or beta | 0.3382 |
%95 Ci | [0.21-0.47] unit decrease |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |
PubMed ID | 23382691 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 7q31.1 |
Chromosome id | chr7 |
Chromosome position | 107951753 |
Reported gene | LAMB1 |
Mapped gene | LAMB1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3912 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2072209-G |
SNPs | rs2072209 |
Merged | 0 |
SNP id current | 2072209 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.0581724966622163 |
P value | 0.000008 |
Pvalue mlog | 5.09691001300805 |
P value text | (IGP76) |
Or beta | 0.2906 |
%95 Ci | [0.16-0.42] unit increase |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |