SNP Detail For rs2071543
1.Mapping Information
Human SNP ID rs2071543
Human chromosome chr6
Human SNP position 32843852
Pig chromosome chr7
Pig SNP position 29427999
2.Annotation Information
PubMed ID25305756
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/25305756
StudyDiscovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens.
Disease/TraitIgA nephropathy
Initial sample1,194 Han Chinese ancestry cases, 902 Han Chinese ancestry controls, 1,553 European ancestry cases, 3,050 European ancestry controls
Replication sample2,491 East Asian ancestry cases, 1,780 East Asian ancestry controls, 2,420 European ancestry cases, 7,222 European ancestry controls
Region6p21.32
Chromosome idchr6
Chromosome position32843852
Reported genePSMB9, TAP1, TAP2, PSMB8
Mapped genePSMB8
Upstream gene id
Downstream gene id
SNP gene ids5696
Upstream gene distance
Downstream gene distance
SNP risk allelers2071543-G
SNPsrs2071543
Merged0
SNP id current2071543
Contextmissense_variant
Intergenic0
Allele frequency0.8
P value0.000000002
Pvalue mlog8.69897000433601
P value text(East Asian)
Or beta1.41
%95 Ci[NR]
PlatformIllumina [> 1000000] (imputed)
CNVN
Mapped traitIGA glomerulonephritis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004194
Study accessionGCST002655