Human SNP ID | rs2071543 |
---|---|
Human chromosome | chr6 |
Human SNP position | 32843852 |
Pig chromosome | chr7 |
Pig SNP position | 29427999 |
PubMed ID | 25305756 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/25305756 |
Study | Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens. |
Disease/Trait | IgA nephropathy |
Initial sample | 1,194 Han Chinese ancestry cases, 902 Han Chinese ancestry controls, 1,553 European ancestry cases, 3,050 European ancestry controls |
Replication sample | 2,491 East Asian ancestry cases, 1,780 East Asian ancestry controls, 2,420 European ancestry cases, 7,222 European ancestry controls |
Region | 6p21.32 |
Chromosome id | chr6 |
Chromosome position | 32843852 |
Reported gene | PSMB9, TAP1, TAP2, PSMB8 |
Mapped gene | PSMB8 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 5696 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2071543-G |
SNPs | rs2071543 |
Merged | 0 |
SNP id current | 2071543 |
Context | missense_variant |
Intergenic | 0 |
Allele frequency | 0.8 |
P value | 0.000000002 |
Pvalue mlog | 8.69897000433601 |
P value text | (East Asian) |
Or beta | 1.41 |
%95 Ci | [NR] |
Platform | Illumina [> 1000000] (imputed) |
CNV | N |
Mapped trait | IGA glomerulonephritis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004194 |
Study accession | GCST002655 |