Human SNP ID | rs2071449 |
---|---|
Human chromosome | chr12 |
Human SNP position | 54034227 |
Pig chromosome | chr5 |
Pig SNP position | 20148196 |
PubMed ID | 25673412 |
---|---|
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/25673412 |
Study | New genetic loci link adipose and insulin biology to body fat distribution. |
Disease/Trait | Waist-to-hip ratio adjusted for body mass index |
Initial sample | up to 56,910 European ancestry men, up to 86,570 European ancestry women |
Replication sample | up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr |
Region | 12q13.13 |
Chromosome id | chr12 |
Chromosome position | 54034227 |
Reported gene | HOXC4, HOXC6 |
Mapped gene | HOXC4, HOXC5 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3221, 3222 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2071449-A |
SNPs | rs2071449 |
Merged | 0 |
SNP id current | 2071449 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.3669 |
P value | 0.00000004 |
Pvalue mlog | 7.39794000867203 |
P value text | (EA, women) |
Or beta | 0.0265 |
%95 Ci | [0.017-0.036] unit increase |
Platform | Affymetrix, Illumina, Perlegen [up to 2542447] (imputed) |
CNV | N |
Mapped trait | waist-hip ratio, body mass index |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340 |
Study accession | GCST002782 |
PubMed ID | 25673412 |
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/25673412 |
Study | New genetic loci link adipose and insulin biology to body fat distribution. |
Disease/Trait | Waist-to-hip ratio adjusted for body mass index |
Initial sample | up to 56,910 European ancestry men, up to 86,570 European ancestry women |
Replication sample | up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr |
Region | 12q13.13 |
Chromosome id | chr12 |
Chromosome position | 54034227 |
Reported gene | HOXC4, HOXC6 |
Mapped gene | HOXC4, HOXC5 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3221, 3222 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2071449-A |
SNPs | rs2071449 |
Merged | 0 |
SNP id current | 2071449 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.3715 |
P value | 0.00000003 |
Pvalue mlog | 7.52287874528033 |
P value text | (EA, men) |
Or beta | 0.0287 |
%95 Ci | [0.019-0.039] unit increase |
Platform | Affymetrix, Illumina, Perlegen [up to 2542447] (imputed) |
CNV | N |
Mapped trait | waist-hip ratio, body mass index |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340 |
Study accession | GCST002782 |
PubMed ID | 25673412 |
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/25673412 |
Study | New genetic loci link adipose and insulin biology to body fat distribution. |
Disease/Trait | Waist-to-hip ratio adjusted for body mass index |
Initial sample | up to 56,910 European ancestry men, up to 86,570 European ancestry women |
Replication sample | up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr |
Region | 12q13.13 |
Chromosome id | chr12 |
Chromosome position | 54034227 |
Reported gene | HOXC4, HOXC6 |
Mapped gene | HOXC4, HOXC5 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3221, 3222 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2071449-A |
SNPs | rs2071449 |
Merged | 0 |
SNP id current | 2071449 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.3692 |
P value | 0.00000000000003 |
Pvalue mlog | 13.5228787452803 |
P value text | (EA) |
Or beta | 0.0276 |
%95 Ci | [0.021-0.035] unit increase |
Platform | Affymetrix, Illumina, Perlegen [up to 2542447] (imputed) |
CNV | N |
Mapped trait | waist-hip ratio, body mass index |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340 |
Study accession | GCST002782 |
PubMed ID | 25673412 |
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/25673412 |
Study | New genetic loci link adipose and insulin biology to body fat distribution. |
Disease/Trait | Waist-to-hip ratio adjusted for body mass index |
Initial sample | up to 56,910 European ancestry men, up to 86,570 European ancestry women |
Replication sample | up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr |
Region | 12q13.13 |
Chromosome id | chr12 |
Chromosome position | 54034227 |
Reported gene | HOXC4, HOXC6 |
Mapped gene | HOXC4, HOXC5 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3221, 3222 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2071449-A |
SNPs | rs2071449 |
Merged | 0 |
SNP id current | 2071449 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.368 |
P value | 0.0000002 |
Pvalue mlog | 6.69897000433601 |
P value text | (men) |
Or beta | 0.0265 |
%95 Ci | [0.017-0.036] unit increase |
Platform | Affymetrix, Illumina, Perlegen [up to 2542447] (imputed) |
CNV | N |
Mapped trait | waist-hip ratio, body mass index |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340 |
Study accession | GCST002782 |
PubMed ID | 25673412 |
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/25673412 |
Study | New genetic loci link adipose and insulin biology to body fat distribution. |
Disease/Trait | Waist-to-hip ratio adjusted for body mass index |
Initial sample | up to 56,910 European ancestry men, up to 86,570 European ancestry women |
Replication sample | up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr |
Region | 12q13.13 |
Chromosome id | chr12 |
Chromosome position | 54034227 |
Reported gene | HOXC4, HOXC6 |
Mapped gene | HOXC4, HOXC5 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3221, 3222 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2071449-A |
SNPs | rs2071449 |
Merged | 0 |
SNP id current | 2071449 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.3623 |
P value | 0.00000005 |
Pvalue mlog | 7.30102999566398 |
P value text | (women) |
Or beta | 0.0261 |
%95 Ci | [0.017-0.036] unit increase |
Platform | Affymetrix, Illumina, Perlegen [up to 2542447] (imputed) |
CNV | N |
Mapped trait | waist-hip ratio, body mass index |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340 |
Study accession | GCST002782 |
PubMed ID | 25673412 |
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/25673412 |
Study | New genetic loci link adipose and insulin biology to body fat distribution. |
Disease/Trait | Waist-to-hip ratio adjusted for body mass index |
Initial sample | up to 56,910 European ancestry men, up to 86,570 European ancestry women |
Replication sample | up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr |
Region | 12q13.13 |
Chromosome id | chr12 |
Chromosome position | 54034227 |
Reported gene | HOXC4, HOXC6 |
Mapped gene | HOXC4, HOXC5 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3221, 3222 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2071449-A |
SNPs | rs2071449 |
Merged | 0 |
SNP id current | 2071449 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.3637 |
P value | 0.0000000000003 |
Pvalue mlog | 12.5228787452803 |
P value text | |
Or beta | 0.0261 |
%95 Ci | [0.019-0.033] unit increase |
Platform | Affymetrix, Illumina, Perlegen [up to 2542447] (imputed) |
CNV | N |
Mapped trait | waist-hip ratio, body mass index |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340 |
Study accession | GCST002782 |