Human SNP ID | rs2066807 |
---|---|
Human chromosome | chr12 |
Human SNP position | 56346898 |
Pig chromosome | chr5 |
Pig SNP position | 23283451 |
PubMed ID | 20881960 |
---|---|
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/20881960 |
Study | Hundreds of variants clustered in genomic loci and biological pathways affect human height. |
Disease/Trait | Height |
Initial sample | 133,653 European ancestry individuals |
Replication sample | 50,074 European ancestry individuals |
Region | 12q13.3 |
Chromosome id | chr12 |
Chromosome position | 56346898 |
Reported gene | STAT2 |
Mapped gene | STAT2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 6773 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2066807-C |
SNPs | rs2066807 |
Merged | 0 |
SNP id current | 2066807 |
Context | missense_variant |
Intergenic | 0 |
Allele frequency | 0.93 |
P value | 0.0000000000001 |
Pvalue mlog | 13 |
P value text | |
Or beta | 0.054 |
%95 Ci | [NR] unit decrease |
Platform | Affymetrix, Illumina [2834208] (imputed) |
CNV | N |
Mapped trait | body height |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004339 |
Study accession | GCST000817 |
PubMed ID | 25903422 |
Journal | Nat Commun |
Link | www.ncbi.nlm.nih.gov/pubmed/25903422 |
Study | Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility. |
Disease/Trait | Psoriasis |
Initial sample | 3,496 European ancestry cases, 5,186 European ancestry controls, 1,588 Chinese ancestry cases, 3,546 Chinese ancestry controls |
Replication sample | 5,134 European ancestry cases, 5,633 European ancestry controls, 5,151 Chinese ancestry cases, 5,152 Chinese ancestry controls |
Region | 12q13.3 |
Chromosome id | chr12 |
Chromosome position | 56346898 |
Reported gene | IL23A, STAT2 |
Mapped gene | STAT2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 6773 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2066807-G |
SNPs | rs2066807 |
Merged | 0 |
SNP id current | 2066807 |
Context | missense_variant |
Intergenic | 0 |
Allele frequency | 0.932351 |
P value | 0.0000000001 |
Pvalue mlog | 10 |
P value text | (EA) |
Or beta | 1.55 |
%95 Ci | [1.35-1.77] |
Platform | Illumina [up to 4778154] (imputed) |
CNV | N |
Mapped trait | psoriasis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000676 |
Study accession | GCST002874 |
PubMed ID | 25903422 |
Journal | Nat Commun |
Link | www.ncbi.nlm.nih.gov/pubmed/25903422 |
Study | Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility. |
Disease/Trait | Psoriasis |
Initial sample | 3,496 European ancestry cases, 5,186 European ancestry controls, 1,588 Chinese ancestry cases, 3,546 Chinese ancestry controls |
Replication sample | 5,134 European ancestry cases, 5,633 European ancestry controls, 5,151 Chinese ancestry cases, 5,152 Chinese ancestry controls |
Region | 12q13.3 |
Chromosome id | chr12 |
Chromosome position | 56346898 |
Reported gene | IL23A, STAT2 |
Mapped gene | STAT2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 6773 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2066807-G |
SNPs | rs2066807 |
Merged | 0 |
SNP id current | 2066807 |
Context | missense_variant |
Intergenic | 0 |
Allele frequency | 0.932351 |
P value | 0.000000000005 |
Pvalue mlog | 11.3010299956639 |
P value text | |
Or beta | 1.4 |
%95 Ci | [1.27-1.54] |
Platform | Illumina [up to 4778154] (imputed) |
CNV | N |
Mapped trait | psoriasis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000676 |
Study accession | GCST002874 |