SNP Detail For rs2066807
1.Mapping Information
Human SNP ID rs2066807
Human chromosome chr12
Human SNP position 56346898
Pig chromosome chr5
Pig SNP position 23283451
2.Annotation Information
PubMed ID20881960
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/20881960
StudyHundreds of variants clustered in genomic loci and biological pathways affect human height.
Disease/TraitHeight
Initial sample133,653 European ancestry individuals
Replication sample50,074 European ancestry individuals
Region12q13.3
Chromosome idchr12
Chromosome position56346898
Reported geneSTAT2
Mapped geneSTAT2
Upstream gene id
Downstream gene id
SNP gene ids6773
Upstream gene distance
Downstream gene distance
SNP risk allelers2066807-C
SNPsrs2066807
Merged0
SNP id current2066807
Contextmissense_variant
Intergenic0
Allele frequency0.93
P value0.0000000000001
Pvalue mlog13
P value text
Or beta0.054
%95 Ci[NR] unit decrease
PlatformAffymetrix, Illumina [2834208] (imputed)
CNVN
Mapped traitbody height
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004339
Study accessionGCST000817
PubMed ID25903422
JournalNat Commun
Linkwww.ncbi.nlm.nih.gov/pubmed/25903422
StudyGenome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility.
Disease/TraitPsoriasis
Initial sample3,496 European ancestry cases, 5,186 European ancestry controls, 1,588 Chinese ancestry cases, 3,546 Chinese ancestry controls
Replication sample5,134 European ancestry cases, 5,633 European ancestry controls, 5,151 Chinese ancestry cases, 5,152 Chinese ancestry controls
Region12q13.3
Chromosome idchr12
Chromosome position56346898
Reported geneIL23A, STAT2
Mapped geneSTAT2
Upstream gene id
Downstream gene id
SNP gene ids6773
Upstream gene distance
Downstream gene distance
SNP risk allelers2066807-G
SNPsrs2066807
Merged0
SNP id current2066807
Contextmissense_variant
Intergenic0
Allele frequency0.932351
P value0.0000000001
Pvalue mlog10
P value text(EA)
Or beta1.55
%95 Ci[1.35-1.77]
PlatformIllumina [up to 4778154] (imputed)
CNVN
Mapped traitpsoriasis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000676
Study accessionGCST002874
PubMed ID25903422
JournalNat Commun
Linkwww.ncbi.nlm.nih.gov/pubmed/25903422
StudyGenome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility.
Disease/TraitPsoriasis
Initial sample3,496 European ancestry cases, 5,186 European ancestry controls, 1,588 Chinese ancestry cases, 3,546 Chinese ancestry controls
Replication sample5,134 European ancestry cases, 5,633 European ancestry controls, 5,151 Chinese ancestry cases, 5,152 Chinese ancestry controls
Region12q13.3
Chromosome idchr12
Chromosome position56346898
Reported geneIL23A, STAT2
Mapped geneSTAT2
Upstream gene id
Downstream gene id
SNP gene ids6773
Upstream gene distance
Downstream gene distance
SNP risk allelers2066807-G
SNPsrs2066807
Merged0
SNP id current2066807
Contextmissense_variant
Intergenic0
Allele frequency0.932351
P value0.000000000005
Pvalue mlog11.3010299956639
P value text
Or beta1.4
%95 Ci[1.27-1.54]
PlatformIllumina [up to 4778154] (imputed)
CNVN
Mapped traitpsoriasis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000676
Study accessionGCST002874