SNP Detail For rs2059614
1.Mapping Information
Human SNP ID rs2059614
Human chromosome chr11
Human SNP position 125389528
Pig chromosome chr9
Pig SNP position 58153438
2.Annotation Information
PubMed ID25890600
JournalJ Natl Cancer Inst
Linkwww.ncbi.nlm.nih.gov/pubmed/25890600
StudyIdentification of novel genetic markers of breast cancer survival.
Disease/TraitBreast cancer (survival)
Initial sample23,059 European ancestry estrogen-receptor positive cases, 6,881 European ancestry estrogen-receptor negative cases, 8,014 European ancestry cases
Replication sample
Region11q24.2
Chromosome idchr11
Chromosome position125389528
Reported geneHEPACAM, HEPN1, CCDC15, SLC37A2, TMEM218, FEZ1, MGC39545, STT3A, CHEK1, ACRV1, PATE1, PATE2, PATE3, PATE4, HYLS1, PKNOX2, ROBO4
Mapped genePKNOX2
Upstream gene id
Downstream gene id
SNP gene ids63876
Upstream gene distance
Downstream gene distance
SNP risk allelers2059614-?
SNPsrs2059614
Merged0
SNP id current2059614
Contextintron_variant
Intergenic0
Allele frequency0.06
P value0.000000001
Pvalue mlog9
P value text(ER -ve)
Or beta1.9
%95 Ci[1.54-2.33]
PlatformAffymetrix, Illumina [9000000] (imputed)
CNVN
Mapped traitestrogen-receptor negative breast cancer, survival time
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_1000650, http://www.ebi.ac.uk/efo/EFO_0000714
Study accessionGCST002861