Human SNP ID | rs2057178 |
---|---|
Human chromosome | chr11 |
Human SNP position | 32342641 |
Pig chromosome | chr2 |
Pig SNP position | 30982551 |
PubMed ID | 22306650 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/22306650 |
Study | Common variants at 11p13 are associated with susceptibility to tuberculosis. |
Disease/Trait | Tuberculosis |
Initial sample | 1,329 African ancestry cases, 1,847 African ancestry controls |
Replication sample | 2,024 African ancestry cases, 5,154 African ancestry controls, 1,025 Indonesian ancestry cases, 983 Indonesian ancestry controls, 4,441 European ancestry cases, 5,874 European ancestry controls |
Region | 11p13 |
Chromosome id | chr11 |
Chromosome position | 32342641 |
Reported gene | WT1 |
Mapped gene | RCN1 - WT1 |
Upstream gene id | 5954 |
Downstream gene id | 7490 |
SNP gene ids | |
Upstream gene distance | 236915 |
Downstream gene distance | 45134 |
SNP risk allele | rs2057178-? |
SNPs | rs2057178 |
Merged | 0 |
SNP id current | 2057178 |
Context | intron_variant |
Intergenic | 1 |
Allele frequency | NR |
P value | 0.00000000003 |
Pvalue mlog | 10.5228787452803 |
P value text | |
Or beta | 1.1 |
%95 Ci | [1.01-1.22] Russian samples |
Platform | Affymetrix [793964] |
CNV | N |
Mapped trait | Tuberculosis |
Mapped trait URI | http://www.orpha.net/ORDO/Orphanet_3389 |
Study accession | GCST001398 |
PubMed ID | 24057671 |
Journal | Hum Mol Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24057671 |
Study | Genome-wide association study of ancestry-specific TB risk in the South African Coloured population. |
Disease/Trait | Tuberculosis |
Initial sample | 642 South African coloured cases, 91 South African coloured controls |
Replication sample | NA |
Region | 11p13 |
Chromosome id | chr11 |
Chromosome position | 32342641 |
Reported gene | WT1 |
Mapped gene | RCN1 - WT1 |
Upstream gene id | 5954 |
Downstream gene id | 7490 |
SNP gene ids | |
Upstream gene distance | 236915 |
Downstream gene distance | 45134 |
SNP risk allele | rs2057178-A |
SNPs | rs2057178 |
Merged | 0 |
SNP id current | 2057178 |
Context | intron_variant |
Intergenic | 1 |
Allele frequency | 0.92 |
P value | 0.000003 |
Pvalue mlog | 5.52287874528033 |
P value text | |
Or beta | 1.6129 |
%95 Ci | [NR] |
Platform | Affymetrix [up to 4467279] (imputed) |
CNV | N |
Mapped trait | Tuberculosis |
Mapped trait URI | http://www.orpha.net/ORDO/Orphanet_3389 |
Study accession | GCST002198 |
PubMed ID | 24057671 |
Journal | Hum Mol Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24057671 |
Study | Genome-wide association study of ancestry-specific TB risk in the South African Coloured population. |
Disease/Trait | Tuberculosis |
Initial sample | 642 South African coloured cases, 91 South African coloured controls, (see Thye 2010) |
Replication sample | NA |
Region | 11p13 |
Chromosome id | chr11 |
Chromosome position | 32342641 |
Reported gene | WT1 |
Mapped gene | RCN1 - WT1 |
Upstream gene id | 5954 |
Downstream gene id | 7490 |
SNP gene ids | |
Upstream gene distance | 236915 |
Downstream gene distance | 45134 |
SNP risk allele | rs2057178-? |
SNPs | rs2057178 |
Merged | 0 |
SNP id current | 2057178 |
Context | intron_variant |
Intergenic | 1 |
Allele frequency | NR |
P value | 0.000000000001 |
Pvalue mlog | 12 |
P value text | (binary model) |
Or beta | |
%95 Ci | |
Platform | Affymetrix [1009364] (imputed) |
CNV | N |
Mapped trait | Tuberculosis |
Mapped trait URI | http://www.orpha.net/ORDO/Orphanet_3389 |
Study accession | GCST002197 |