SNP Detail For rs2043085
1.Mapping Information
Human SNP ID rs2043085
Human chromosome chr15
Human SNP position 58388755
Pig chromosome chr1
Pig SNP position 125713178
2.Annotation Information
PubMed ID21386085
JournalDiabetes
Linkwww.ncbi.nlm.nih.gov/pubmed/21386085
StudyA bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.
Disease/TraitMetabolic syndrome (bivariate traits)
Initial sample22,161 European ancestry individuals
Replication sampleNA
Region15q21.3
Chromosome idchr15
Chromosome position58388755
Reported geneLIPC
Mapped geneLOC101928635
Upstream gene id
Downstream gene id
SNP gene ids101928635
Upstream gene distance
Downstream gene distance
SNP risk allelers2043085-A
SNPsrs2043085
Merged0
SNP id current2043085
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.00000001
Pvalue mlog8
P value text(HDLC-GLUC)
Or beta0.17
%95 Ci[0.11-0.23] unit decrease
PlatformAffymetrix, Illumina [~ 2500000] (imputed)
CNVN
Mapped traitmetabolic syndrome
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000195
Study accessionGCST001007
PubMed ID24386095
JournalPLoS One
Linkwww.ncbi.nlm.nih.gov/pubmed/24386095
StudyA genome wide association study identifies common variants associated with lipid levels in the Chinese population.
Disease/TraitLipid traits
Initial sample3,451 Han Chinese ancestry individuals
Replication sample8,830 Han Chinese ancestry individuals
Region15q21.3
Chromosome idchr15
Chromosome position58388755
Reported geneLIPC
Mapped geneLOC101928635
Upstream gene id
Downstream gene id
SNP gene ids101928635
Upstream gene distance
Downstream gene distance
SNP risk allelers2043085-T
SNPsrs2043085
Merged0
SNP id current2043085
Contextintron_variant
Intergenic0
Allele frequency0.47
P value0.00000002
Pvalue mlog7.69897000433601
P value text(HDL)
Or beta0.012
%95 Ci[0.00024-0.02376] mmol/L increase
PlatformAffymetrix, Illumina [up to 2249917] (imputed)
CNVN
Mapped traithigh density lipoprotein cholesterol measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004612
Study accessionGCST002321
PubMed ID26691988
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26691988
StudyA large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.
Disease/TraitAdvanced age-related macular degeneration
Initial sample16,144 European ancestry cases, 17,832 European ancestry controls
Replication sample473 Asian ancestry cases, 1,099 Asian ancestry controls, 52 African ancestry cases, 361 African ancestry cases, 254 other non-European ancestry cases, 694 other non-European ancestry controls
Region15q21.3
Chromosome idchr15
Chromosome position58388755
Reported geneLIPC
Mapped geneLOC101928635
Upstream gene id
Downstream gene id
SNP gene ids101928635
Upstream gene distance
Downstream gene distance
SNP risk allelers2043085-?
SNPsrs2043085
Merged0
SNP id current2043085
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.000000000000004
Pvalue mlog14.397940008672
P value text(EA)
Or beta1.1494253
%95 Ci
PlatformIllumina [12023830] (imputed)
CNVN
Mapped traitage-related macular degeneration, wet macular degeneration
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001365, http://www.ebi.ac.uk/efo/EFO_0004683
Study accessionGCST003219