Human SNP ID | rs2020921 |
---|---|
Human chromosome | chr8 |
Human SNP position | 42187447 |
Pig chromosome | chr17 |
Pig SNP position | 13179377 |
PubMed ID | 24578379 |
---|---|
Journal | Arterioscler Thromb Vasc Biol |
Link | www.ncbi.nlm.nih.gov/pubmed/24578379 |
Study | Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2. |
Disease/Trait | Plasma plasminogen activator levels |
Initial sample | 26,217 European ancestry individuals, 712 Orcadian individuals |
Replication sample | 4,487 European ancestry individuals |
Region | 8p11.21 |
Chromosome id | chr8 |
Chromosome position | 42187447 |
Reported gene | PLAT |
Mapped gene | PLAT |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 5327 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs2020921-G |
SNPs | rs2020921 |
Merged | 0 |
SNP id current | 2020921 |
Context | missense_variant |
Intergenic | 0 |
Allele frequency | 0.95 |
P value | 0.00000002 |
Pvalue mlog | 7.69897000433601 |
P value text | |
Or beta | 0.067 |
%95 Ci | [0.043-0.091] unit increase |
Platform | Affymetrix, Illumina [2455857] (imputed) |
CNV | N |
Mapped trait | tissue plasminogen activator measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004791 |
Study accession | GCST002374 |