SNP Detail For rs2016325
1.Mapping Information
Human SNP ID rs2016325
Human chromosome chr7
Human SNP position 66858513
Pig chromosome chr3
Pig SNP position 11500010
2.Annotation Information
PubMed ID26121980
JournalBMC Genomics
Linkwww.ncbi.nlm.nih.gov/pubmed/26121980
StudyGenome-wide association analysis identified splicing single nucleotide polymorphism in CFLAR predictive of triptolide chemo-sensitivity.
Disease/TraitTriptolide cytotoxicity
Initial sample55 European ancestry lymphoblastoid cell lines
Replication sampleNA
Region7q11.21
Chromosome idchr7
Chromosome position66858513
Reported geneintergenic
Mapped geneLOC101929580
Upstream gene id
Downstream gene id
SNP gene ids101929580
Upstream gene distance
Downstream gene distance
SNP risk allelers2016325-?
SNPsrs2016325
Merged
SNP id current2016325
Contextdownstream_gene_variant
Intergenic0
Allele frequencyNR
P value0.000008
Pvalue mlog5.09691001300805
P value text
Or beta0.56
%95 Ciunit increase
PlatformNR [at least 1978803] (imputed)
CNVN
Mapped traitresponse to triptolide, cytotoxicity measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0007662, http://www.ebi.ac.uk/efo/EFO_0006952
Study accessionGCST003008