SNP Detail For rs1996371
1.Mapping Information
Human SNP ID rs1996371
Human chromosome chr15
Human SNP position 78664464
Pig chromosome chr7
Pig SNP position 52860367
2.Annotation Information
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region15q25.1
Chromosome idchr15
Chromosome position78664464
Reported geneIntergenic
Mapped geneRPL18P11 - LOC105370913
Upstream gene id390612
Downstream gene id105370913
SNP gene ids
Upstream gene distance2823
Downstream gene distance28362
SNP risk allelers1996371-T
SNPsrs1996371
Merged0
SNP id current1996371
Contextintron_variant
Intergenic1
Allele frequency0.568
P value0.0000001
Pvalue mlog7
P value text
Or beta0.051
%95 CiNR unit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitforced expiratory volume, response to bronchodilator
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366
Study accessionGCST003262
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region15q25.1
Chromosome idchr15
Chromosome position78664464
Reported geneIntergenic
Mapped geneRPL18P11 - LOC105370913
Upstream gene id390612
Downstream gene id105370913
SNP gene ids
Upstream gene distance2823
Downstream gene distance28362
SNP risk allelers1996371-T
SNPsrs1996371
Merged0
SNP id current1996371
Contextintron_variant
Intergenic1
Allele frequency0.57
P value0.00000004
Pvalue mlog7.39794000867203
P value text
Or beta0.011
%95 Ciunit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003264