SNP Detail For rs1980422
1.Mapping Information
Human SNP ID rs1980422
Human chromosome chr2
Human SNP position 203745673
Pig chromosome chr15
Pig SNP position 118511716
2.Annotation Information
PubMed ID24390342
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/24390342
StudyGenetics of rheumatoid arthritis contributes to biology and drug discovery.
Disease/TraitRheumatoid arthritis
Initial sampleup to 14,361 European ancestry cases, up to 42,923 European ancestry controls, up to 4,873 East Asian ancestry cases, up to 17,642 East Asian ancestry controls
Replication sampleup to 3,775 European ancestry cases, up to 5,801 European ancestry controls, up to 6,871 East Asian ancestry cases, up to 6,392 East Asian ancestry controls
Region2q33.2
Chromosome idchr2
Chromosome position203745673
Reported geneCD28
Mapped geneCD28 - KRT18P39
Upstream gene id940
Downstream gene id344462
SNP gene ids
Upstream gene distance6761
Downstream gene distance18560
SNP risk allelers1980422-C
SNPsrs1980422
Merged0
SNP id current1980422
Contextintergenic_variant
Intergenic1
Allele frequency0.19
P value0.00000000000003
Pvalue mlog13.5228787452803
P value text
Or beta1.12
%95 Ci[1.09-1.16]
PlatformAffymetrix, Illumina [up to 9739303] (imputed)
CNVN
Mapped traitrheumatoid arthritis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000685
Study accessionGCST002318
PubMed ID24390342
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/24390342
StudyGenetics of rheumatoid arthritis contributes to biology and drug discovery.
Disease/TraitRheumatoid arthritis
Initial sampleup to 14,361 European ancestry cases, up to 42,923 European ancestry controls, up to 4,873 East Asian ancestry cases, up to 17,642 East Asian ancestry controls
Replication sampleup to 3,775 European ancestry cases, up to 5,801 European ancestry controls, up to 6,871 East Asian ancestry cases, up to 6,392 East Asian ancestry controls
Region2q33.2
Chromosome idchr2
Chromosome position203745673
Reported geneCD28
Mapped geneCD28 - KRT18P39
Upstream gene id940
Downstream gene id344462
SNP gene ids
Upstream gene distance6761
Downstream gene distance18560
SNP risk allelers1980422-C
SNPsrs1980422
Merged0
SNP id current1980422
Contextintergenic_variant
Intergenic1
Allele frequency0.24
P value0.0000000000002
Pvalue mlog12.698970004336
P value text(EA)
Or beta1.13
%95 Ci[1.09-1.17]
PlatformAffymetrix, Illumina [up to 9739303] (imputed)
CNVN
Mapped traitrheumatoid arthritis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000685
Study accessionGCST002318