Human SNP ID | rs1980056 |
---|---|
Human chromosome | chr4 |
Human SNP position | 144563771 |
Pig chromosome | chr8 |
Pig SNP position | 89013470 |
PubMed ID | 26634245 |
---|---|
Journal | BMC Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26634245 |
Study | A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. |
Disease/Trait | Post bronchodilator FEV1 |
Initial sample | 10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals |
Replication sample | NA |
Region | 4q31.21 |
Chromosome id | chr4 |
Chromosome position | 144563771 |
Reported gene | Intergenic |
Mapped gene | LOC105377462 - KRT18P51 |
Upstream gene id | 105377462 |
Downstream gene id | 391703 |
SNP gene ids | |
Upstream gene distance | 1266 |
Downstream gene distance | 8467 |
SNP risk allele | rs1980056-A |
SNPs | rs1980056 |
Merged | 0 |
SNP id current | 1980056 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.365 |
P value | 0.0000000000002 |
Pvalue mlog | 12.698970004336 |
P value text | |
Or beta | 0.071 |
%95 Ci | NR unit increase |
Platform | Illumina [NR] (imputed) |
CNV | N |
Mapped trait | forced expiratory volume, response to bronchodilator |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366 |
Study accession | GCST003262 |
PubMed ID | 26634245 |
Journal | BMC Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26634245 |
Study | A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. |
Disease/Trait | Post bronchodilator FEV1/FVC ratio in COPD |
Initial sample | 5,439 European ancestry current and former smoker cases, 821 African American current and former smoker cases |
Replication sample | NA |
Region | 4q31.21 |
Chromosome id | chr4 |
Chromosome position | 144563771 |
Reported gene | Intergenic |
Mapped gene | LOC105377462 - KRT18P51 |
Upstream gene id | 105377462 |
Downstream gene id | 391703 |
SNP gene ids | |
Upstream gene distance | 1266 |
Downstream gene distance | 8467 |
SNP risk allele | rs1980056-A |
SNPs | rs1980056 |
Merged | 0 |
SNP id current | 1980056 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.386 |
P value | 0.000004 |
Pvalue mlog | 5.39794000867203 |
P value text | |
Or beta | 0.011 |
%95 Ci | NR unit increase |
Platform | Illumina [NR] (imputed) |
CNV | N |
Mapped trait | response to bronchodilator, chronic obstructive pulmonary disease, FEV/FEC ratio |
Mapped trait URI | http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0000341, http://www.ebi.ac.uk/efo/EFO_0004713 |
Study accession | GCST003265 |
PubMed ID | 26634245 |
Journal | BMC Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26634245 |
Study | A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. |
Disease/Trait | Post bronchodilator FEV1/FVC ratio |
Initial sample | 10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals |
Replication sample | NA |
Region | 4q31.21 |
Chromosome id | chr4 |
Chromosome position | 144563771 |
Reported gene | Intergenic |
Mapped gene | LOC105377462 - KRT18P51 |
Upstream gene id | 105377462 |
Downstream gene id | 391703 |
SNP gene ids | |
Upstream gene distance | 1266 |
Downstream gene distance | 8467 |
SNP risk allele | rs1980056-A |
SNPs | rs1980056 |
Merged | 0 |
SNP id current | 1980056 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.362 |
P value | 0.00000000000000001 |
Pvalue mlog | 17 |
P value text | |
Or beta | 0.017 |
%95 Ci | unit increase |
Platform | Illumina [NR] (imputed) |
CNV | N |
Mapped trait | response to bronchodilator, FEV/FEC ratio |
Mapped trait URI | http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713 |
Study accession | GCST003264 |