SNP Detail For rs1967017
1.Mapping Information
Human SNP ID rs1967017
Human chromosome chr1
Human SNP position 145711421
Pig chromosome chr4
Pig SNP position 109331255
2.Annotation Information
PubMed ID20884846
JournalCirc Cardiovasc Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/20884846
StudyMultiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors.
Disease/TraitUrate levels
Initial sample28,283 European ancestry individuals
Replication sample22,054 European ancestry individuals
Region1q21.1
Chromosome idchr1
Chromosome position145711421
Reported genePDZK1
Mapped genePDZK1 - CD160
Upstream gene id5174
Downstream gene id11126
SNP gene ids
Upstream gene distance4021
Downstream gene distance8012
SNP risk allelers1967017-T
SNPsrs1967017
Merged0
SNP id current1967017
Contextupstream_gene_variant
Intergenic1
Allele frequency0.47
P value0.00000004
Pvalue mlog7.39794000867203
P value text(Urate)
Or beta3.33
%95 Ci[2.15-4.51] umol/l increase
PlatformAffymetrix, Illumina [~ 2500000] (imputed)
CNVN
Mapped traiturate measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004531
Study accessionGCST000818
PubMed ID25811787
JournalPLoS One
Linkwww.ncbi.nlm.nih.gov/pubmed/25811787
StudyModulation of Genetic Associations with Serum Urate Levels by Body-Mass-Index in Humans.
Disease/TraitUrate levels in overweight individuals
Initial sampleup to 10,058 European ancestry male individuals, up to 7,189 European ancestry female individuals
Replication sampleNA
Region1q21.1
Chromosome idchr1
Chromosome position145711421
Reported genePDZK1
Mapped genePDZK1 - CD160
Upstream gene id5174
Downstream gene id11126
SNP gene ids
Upstream gene distance4021
Downstream gene distance8012
SNP risk allelers1967017-C
SNPsrs1967017
Merged0
SNP id current1967017
Contextupstream_gene_variant
Intergenic1
Allele frequency0.53
P value0.000000005
Pvalue mlog8.30102999566398
P value text
Or beta0.065
%95 Ci[0.043-0.087] kg/m2 decrease
PlatformAffymetrix, Illumina [at least 188473] (imputed)
CNVN
Mapped traiturate measurement, overweight body mass index status
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004531, http://www.ebi.ac.uk/efo/EFO_0005935
Study accessionGCST002829