Human SNP ID | rs1936800 |
---|---|
Human chromosome | chr6 |
Human SNP position | 127114919 |
Pig chromosome | chr1 |
Pig SNP position | 39790681 |
PubMed ID | 22797727 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/22797727 |
Study | Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. |
Disease/Trait | Renal function-related traits (BUN) |
Initial sample | 39,717 East Asian ancestry individuals |
Replication sample | 17,461 East Asian ancestry individuals |
Region | 6q22.33 |
Chromosome id | chr6 |
Chromosome position | 127114919 |
Reported gene | RSPO3 |
Mapped gene | LOC105377989 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 105377989 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs1936800-T |
SNPs | rs1936800 |
Merged | 0 |
SNP id current | 1936800 |
Context | upstream_gene_variant |
Intergenic | 0 |
Allele frequency | 0.5 |
P value | 0.00000000001 |
Pvalue mlog | 11 |
P value text | |
Or beta | 0.0052 |
%95 Ci | [0.0036-0.0068] mg/dl increase |
Platform | Affymetrix, Illumina [2281523] (imputed) |
CNV | N |
Mapped trait | renal system measurement, blood urea nitrogen measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004742, http://www.ebi.ac.uk/efo/EFO_0004741 |
Study accession | GCST001610 |
PubMed ID | 24097068 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24097068 |
Study | Discovery and refinement of loci associated with lipid levels. |
Disease/Trait | HDL cholesterol |
Initial sample | 94,595 European ancestry individuals |
Replication sample | 93,982 European ancestry individuals |
Region | 6q22.33 |
Chromosome id | chr6 |
Chromosome position | 127114919 |
Reported gene | RSPO3 |
Mapped gene | LOC105377989 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 105377989 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs1936800-C |
SNPs | rs1936800 |
Merged | 0 |
SNP id current | 1936800 |
Context | upstream_gene_variant |
Intergenic | 0 |
Allele frequency | 0.49 |
P value | 0.0000000003 |
Pvalue mlog | 9.52287874528033 |
P value text | |
Or beta | 0.02 |
%95 Ci | [NR] unit increase |
Platform | NR [NR] (imputed) |
CNV | N |
Mapped trait | high density lipoprotein cholesterol measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004612 |
Study accession | GCST002223 |
PubMed ID | 24097068 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24097068 |
Study | Discovery and refinement of loci associated with lipid levels. |
Disease/Trait | Triglycerides |
Initial sample | 94,595 European ancestry individuals |
Replication sample | 93,982 European ancestry individuals |
Region | 6q22.33 |
Chromosome id | chr6 |
Chromosome position | 127114919 |
Reported gene | RSPO3 |
Mapped gene | LOC105377989 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 105377989 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs1936800-C |
SNPs | rs1936800 |
Merged | 0 |
SNP id current | 1936800 |
Context | upstream_gene_variant |
Intergenic | 0 |
Allele frequency | 0.49 |
P value | 0.00000003 |
Pvalue mlog | 7.52287874528033 |
P value text | |
Or beta | 0.02 |
%95 Ci | [NR] mg/dL decrease |
Platform | NR [NR] (imputed) |
CNV | N |
Mapped trait | triglyceride measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004530 |
Study accession | GCST002216 |