SNP Detail For rs1936800
1.Mapping Information
Human SNP ID rs1936800
Human chromosome chr6
Human SNP position 127114919
Pig chromosome chr1
Pig SNP position 39790681
2.Annotation Information
PubMed ID22797727
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/22797727
StudyMeta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.
Disease/TraitRenal function-related traits (BUN)
Initial sample39,717 East Asian ancestry individuals
Replication sample17,461 East Asian ancestry individuals
Region6q22.33
Chromosome idchr6
Chromosome position127114919
Reported geneRSPO3
Mapped geneLOC105377989
Upstream gene id
Downstream gene id
SNP gene ids105377989
Upstream gene distance
Downstream gene distance
SNP risk allelers1936800-T
SNPsrs1936800
Merged0
SNP id current1936800
Contextupstream_gene_variant
Intergenic0
Allele frequency0.5
P value0.00000000001
Pvalue mlog11
P value text
Or beta0.0052
%95 Ci[0.0036-0.0068] mg/dl increase
PlatformAffymetrix, Illumina [2281523] (imputed)
CNVN
Mapped traitrenal system measurement, blood urea nitrogen measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004742, http://www.ebi.ac.uk/efo/EFO_0004741
Study accessionGCST001610
PubMed ID24097068
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/24097068
StudyDiscovery and refinement of loci associated with lipid levels.
Disease/TraitHDL cholesterol
Initial sample94,595 European ancestry individuals
Replication sample93,982 European ancestry individuals
Region6q22.33
Chromosome idchr6
Chromosome position127114919
Reported geneRSPO3
Mapped geneLOC105377989
Upstream gene id
Downstream gene id
SNP gene ids105377989
Upstream gene distance
Downstream gene distance
SNP risk allelers1936800-C
SNPsrs1936800
Merged0
SNP id current1936800
Contextupstream_gene_variant
Intergenic0
Allele frequency0.49
P value0.0000000003
Pvalue mlog9.52287874528033
P value text
Or beta0.02
%95 Ci[NR] unit increase
PlatformNR [NR] (imputed)
CNVN
Mapped traithigh density lipoprotein cholesterol measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004612
Study accessionGCST002223
PubMed ID24097068
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/24097068
StudyDiscovery and refinement of loci associated with lipid levels.
Disease/TraitTriglycerides
Initial sample94,595 European ancestry individuals
Replication sample93,982 European ancestry individuals
Region6q22.33
Chromosome idchr6
Chromosome position127114919
Reported geneRSPO3
Mapped geneLOC105377989
Upstream gene id
Downstream gene id
SNP gene ids105377989
Upstream gene distance
Downstream gene distance
SNP risk allelers1936800-C
SNPsrs1936800
Merged0
SNP id current1936800
Contextupstream_gene_variant
Intergenic0
Allele frequency0.49
P value0.00000003
Pvalue mlog7.52287874528033
P value text
Or beta0.02
%95 Ci[NR] mg/dL decrease
PlatformNR [NR] (imputed)
CNVN
Mapped traittriglyceride measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004530
Study accessionGCST002216