SNP Detail For rs1928168
1.Mapping Information
Human SNP ID rs1928168
Human chromosome chr6
Human SNP position 22017509
Pig chromosome chr7
Pig SNP position 18197089
2.Annotation Information
PubMed ID21946350
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/21946350
StudyGenome-wide association and large-scale follow up identifies 16 new loci influencing lung function.
Disease/TraitPulmonary function
Initial sample48,201 European ancestry individuals
Replication sample46,411 European ancestry individuals
Region6p22.3
Chromosome idchr6
Chromosome position22017509
Reported geneAK026189
Mapped geneCASC15
Upstream gene id
Downstream gene id
SNP gene ids401237
Upstream gene distance
Downstream gene distance
SNP risk allelers1928168-T
SNPsrs1928168
Merged0
SNP id current1928168
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.0000002
Pvalue mlog6.69897000433601
P value text(FEV1/FVC)
Or beta0.028
%95 Ci[0.018-0.038] unit increase
PlatformAffymetrix, Illumina [~ 2500000] (imputed)
CNVN
Mapped traitpulmonary function measurement, FEV/FEC ratio
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003892, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST001248
PubMed ID23284291
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23284291
StudyGenome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function.
Disease/TraitPulmonary function (interaction)
Initial sample50,047 European ancestry individuals
Replication sampleNA
Region6p22.3
Chromosome idchr6
Chromosome position22017509
Reported geneSOX4, PRL
Mapped geneCASC15
Upstream gene id
Downstream gene id
SNP gene ids401237
Upstream gene distance
Downstream gene distance
SNP risk allelers1928168-T
SNPsrs1928168
Merged0
SNP id current1928168
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.0000002
Pvalue mlog6.69897000433601
P value text(FEV1/FVC, Ever-smoking)
Or beta
%95 Ci
PlatformNR [~ 2500000] (imputed)
CNVN
Mapped traitFEV/FEC ratio
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST001784