SNP Detail For rs192549394
1.Mapping Information
Human SNP ID rs192549394
Human chromosome chr14
Human SNP position 51827061
Pig chromosome chr1
Pig SNP position 201766227
2.Annotation Information
PubMed ID26252872
JournalPLoS One
Linkwww.ncbi.nlm.nih.gov/pubmed/26252872
StudyVariations in the FRA10AC1 Fragile Site and 15q21 Are Associated with Cerebrospinal Fluid Aå°¾1-42 Level.
Disease/TraitCognitive decline rate in late mild cognitive impairment
Initial sample472 European ancestry cases, 47 cases
Replication sampleNA
Region14q22.1
Chromosome idchr14
Chromosome position51827061
Reported geneFRMD6, GNG2
Mapped geneLOC101927598 - GNG2
Upstream gene id101927598
Downstream gene id54331
SNP gene ids
Upstream gene distance2042
Downstream gene distance20070
SNP risk allelers192549394-G
SNPsrs192549394
Merged
SNP id current192549394
Contextintron_variant
Intergenic1
Allele frequency0.01
P value0.000001
Pvalue mlog6
P value text(EA)
Or beta0.3949
%95 Ci[0.24-0.55] unit increase
PlatformIllumina [~ 9000000] (imputed)
CNVN
Mapped traitcognitive impairment, cognitive decline measurement
Mapped trait URIhttp://purl.obolibrary.org/obo/HP_0100543, http://www.ebi.ac.uk/efo/EFO_0007710
Study accessionGCST003075
PubMed ID26252872
JournalPLoS One
Linkwww.ncbi.nlm.nih.gov/pubmed/26252872
StudyVariations in the FRA10AC1 Fragile Site and 15q21 Are Associated with Cerebrospinal Fluid Aå°¾1-42 Level.
Disease/TraitCognitive decline rate in late mild cognitive impairment
Initial sample472 European ancestry cases, 47 cases
Replication sampleNA
Region14q22.1
Chromosome idchr14
Chromosome position51827061
Reported geneFRMD6, GNG2
Mapped geneLOC101927598 - GNG2
Upstream gene id101927598
Downstream gene id54331
SNP gene ids
Upstream gene distance2042
Downstream gene distance20070
SNP risk allelers192549394-G
SNPsrs192549394
Merged
SNP id current192549394
Contextintron_variant
Intergenic1
Allele frequency0.01
P value0.000002
Pvalue mlog5.69897000433601
P value text
Or beta0.3724
%95 Ci[0.22-0.53] unit increase
PlatformIllumina [~ 9000000] (imputed)
CNVN
Mapped traitcognitive impairment, cognitive decline measurement
Mapped trait URIhttp://purl.obolibrary.org/obo/HP_0100543, http://www.ebi.ac.uk/efo/EFO_0007710
Study accessionGCST003075