SNP Detail For rs192376484
1.Mapping Information
Human SNP ID rs192376484
Human chromosome chr3
Human SNP position 161338027
Pig chromosome chr13
Pig SNP position 109574497
2.Annotation Information
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region3q26.1
Chromosome idchr3
Chromosome position161338027
Reported geneIntergenic
Mapped genePSMC1P7 - SPTSSB
Upstream gene id646085
Downstream gene id165679
SNP gene ids
Upstream gene distance7765
Downstream gene distance6757
SNP risk allelers192376484-A
SNPsrs192376484
Merged0
SNP id current192376484
Contextintergenic_variant
Intergenic1
Allele frequency1
P value0.0000005
Pvalue mlog6.30102999566398
P value text(AA)
Or beta2.355
%95 CiNR unit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitforced expiratory volume, response to bronchodilator
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366
Study accessionGCST003262
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region3q26.1
Chromosome idchr3
Chromosome position161338027
Reported geneIntergenic
Mapped genePSMC1P7 - SPTSSB
Upstream gene id646085
Downstream gene id165679
SNP gene ids
Upstream gene distance7765
Downstream gene distance6757
SNP risk allelers192376484-A
SNPsrs192376484
Merged0
SNP id current192376484
Contextintergenic_variant
Intergenic1
Allele frequency1
P value0.000002
Pvalue mlog5.69897000433601
P value text(AA)
Or beta0.445
%95 Ciunit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003264