SNP Detail For rs191739273
1.Mapping Information
Human SNP ID rs191739273
Human chromosome chr14
Human SNP position 45943510
Pig chromosome chr1
Pig SNP position 195959213
2.Annotation Information
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region14q21.2
Chromosome idchr14
Chromosome position45943510
Reported geneIntergenic
Mapped geneLOC105378177 - LINC00871
Upstream gene id105378177
Downstream gene id100506412
SNP gene ids
Upstream gene distance86468
Downstream gene distance120649
SNP risk allelers191739273-G
SNPsrs191739273
Merged0
SNP id current191739273
Contextintron_variant
Intergenic1
Allele frequency1
P value0.0000002
Pvalue mlog6.69897000433601
P value text(AA)
Or beta2.177
%95 CiNR unit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitforced expiratory volume, response to bronchodilator
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366
Study accessionGCST003262
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region14q21.2
Chromosome idchr14
Chromosome position45943510
Reported geneIntergenic
Mapped geneLOC105378177 - LINC00871
Upstream gene id105378177
Downstream gene id100506412
SNP gene ids
Upstream gene distance86468
Downstream gene distance120649
SNP risk allelers191739273-G
SNPsrs191739273
Merged0
SNP id current191739273
Contextintron_variant
Intergenic1
Allele frequency1
P value0.000000003
Pvalue mlog8.52287874528033
P value text(AA)
Or beta0.495
%95 Ciunit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003264