SNP Detail For rs1914816
1.Mapping Information
Human SNP ID rs1914816
Human chromosome chr15
Human SNP position 76254592
Pig chromosome chr7
Pig SNP position 60991430
2.Annotation Information
PubMed ID22491018
JournalPharmacogenomics J
Linkwww.ncbi.nlm.nih.gov/pubmed/22491018
StudyGenome-wide association analysis implicates the involvement of eight loci with response to tocilizumab for the treatment of rheumatoid arthritis.
Disease/TraitResponse to tocilizumab in rheumatoid arthritis
Initial sample1,157 European and other ancestry rheumatoid arthritis cases
Replication sample526 European and other ancestry rheumatoid arthritis cases
Region15q24.2
Chromosome idchr15
Chromosome position76254592
Reported geneETFA
Mapped geneETFA
Upstream gene id
Downstream gene id
SNP gene ids2108
Upstream gene distance
Downstream gene distance
SNP risk allelers1914816-?
SNPsrs1914816
Merged0
SNP id current1914816
Contextintron_variant
Intergenic0
Allele frequency0.3
P value0.0000007
Pvalue mlog6.15490195998574
P value text(CDAS28, EA, RF-)
Or beta0.87
%95 Ci[NR] unit increase
PlatformIllumina [534053]
CNVN
Mapped traitrheumatoid arthritis, response to drug
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000685, http://purl.obolibrary.org/obo/GO_0042493
Study accessionGCST001476