SNP Detail For rs1910505
1.Mapping Information
Human SNP ID rs1910505
Human chromosome chr11
Human SNP position 11087692
Pig chromosome chr2
Pig SNP position 51683165
2.Annotation Information
PubMed ID26031901
JournalPharmacogenomics J
Linkwww.ncbi.nlm.nih.gov/pubmed/26031901
StudyGenome-wide association study of leukotriene modifier response in asthma.
Disease/TraitResponse to zileuton treatment in asthma (FEV1 change interaction)
Initial sample160 European and other ancestry zileuton-treated cases, 144 European and other ancestry placebo-controlled cases
Replication sample149 European and other ancestry zileuton-treated cases, 73 European and other ancestry placebo-controlled cases
Region11p15.4
Chromosome idchr11
Chromosome position11087692
Reported geneintergenic
Mapped geneLOC105376550
Upstream gene id
Downstream gene id
SNP gene ids105376550
Upstream gene distance
Downstream gene distance
SNP risk allelers1910505-?
SNPsrs1910505
Merged
SNP id current1910505
Contextintergenic_variant
Intergenic0
Allele frequencyNR
P value0.000004
Pvalue mlog5.39794000867203
P value text(Additive model)
Or beta0.3
%95 Ciunit increase
PlatformIllumina [542562]
CNVN
Mapped traitFEV change measurement, response to zileuton, asthma
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005921, http://www.ebi.ac.uk/efo/EFO_0007676, http://www.ebi.ac.uk/efo/EFO_0000270
Study accessionGCST002951