SNP Detail For rs190262953
1.Mapping Information
Human SNP ID rs190262953
Human chromosome chr12
Human SNP position 91432197
Pig chromosome chr5
Pig SNP position 95875345
2.Annotation Information
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region12q21.33
Chromosome idchr12
Chromosome position91432197
Reported geneIntergenic
Mapped geneLOC105369896
Upstream gene id
Downstream gene id
SNP gene ids105369896
Upstream gene distance
Downstream gene distance
SNP risk allelers190262953-T
SNPsrs190262953
Merged0
SNP id current190262953
Contextregulatory_region_variant
Intergenic0
Allele frequency1
P value0.000002
Pvalue mlog5.69897000433601
P value text(AA)
Or beta2.16
%95 CiNR unit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitforced expiratory volume, response to bronchodilator
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366
Study accessionGCST003262
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region12q21.33
Chromosome idchr12
Chromosome position91432197
Reported geneIntergenic
Mapped geneLOC105369896
Upstream gene id
Downstream gene id
SNP gene ids105369896
Upstream gene distance
Downstream gene distance
SNP risk allelers190262953-T
SNPsrs190262953
Merged0
SNP id current190262953
Contextregulatory_region_variant
Intergenic0
Allele frequency1
P value0.000003
Pvalue mlog5.52287874528033
P value text(AA)
Or beta0.427
%95 Ciunit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003264