SNP Detail For rs1874791
1.Mapping Information
Human SNP ID rs1874791
Human chromosome chr1
Human SNP position 67340749
Pig chromosome chr6
Pig SNP position 134136521
2.Annotation Information
PubMed ID26502338
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26502338
StudyGenetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.
Disease/TraitSystemic lupus erythematosus
Initial sample5,201 European ancestry cases, 9,066 European ancestry controls
Replication sample2,018 European ancestry cases, 6,925 European ancestry controls
Region1p31.3
Chromosome idchr1
Chromosome position67340749
Reported geneIL12RB2
Mapped geneIL12RB2
Upstream gene id
Downstream gene id
SNP gene ids3595
Upstream gene distance
Downstream gene distance
SNP risk allelers1874791-A
SNPsrs1874791
Merged
SNP id current1874791
Contextintron_variant
Intergenic0
Allele frequency
P value0.0000003
Pvalue mlog6.52287874528033
P value text
Or beta1.14
%95 Ci[1.09鈥?.20]
PlatformIllumina [644674]
CNVN
Mapped traitsystemic lupus erythematosus
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0002690
Study accessionGCST003155