Human SNP ID | rs1874791 |
---|---|
Human chromosome | chr1 |
Human SNP position | 67340749 |
Pig chromosome | chr6 |
Pig SNP position | 134136521 |
PubMed ID | 26502338 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26502338 |
Study | Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus. |
Disease/Trait | Systemic lupus erythematosus |
Initial sample | 5,201 European ancestry cases, 9,066 European ancestry controls |
Replication sample | 2,018 European ancestry cases, 6,925 European ancestry controls |
Region | 1p31.3 |
Chromosome id | chr1 |
Chromosome position | 67340749 |
Reported gene | IL12RB2 |
Mapped gene | IL12RB2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3595 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs1874791-A |
SNPs | rs1874791 |
Merged | |
SNP id current | 1874791 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | |
P value | 0.0000003 |
Pvalue mlog | 6.52287874528033 |
P value text | |
Or beta | 1.14 |
%95 Ci | [1.09鈥?.20] |
Platform | Illumina [644674] |
CNV | N |
Mapped trait | systemic lupus erythematosus |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0002690 |
Study accession | GCST003155 |