SNP Detail For rs1872085
1.Mapping Information
Human SNP ID rs1872085
Human chromosome chr17
Human SNP position 73531941
Pig chromosome chr12
Pig SNP position 7722466
2.Annotation Information
PubMed ID26031901
JournalPharmacogenomics J
Linkwww.ncbi.nlm.nih.gov/pubmed/26031901
StudyGenome-wide association study of leukotriene modifier response in asthma.
Disease/TraitResponse to zileuton treatment in asthma (FEV1 change interaction)
Initial sample160 European and other ancestry zileuton-treated cases, 144 European and other ancestry placebo-controlled cases
Replication sample149 European and other ancestry zileuton-treated cases, 73 European and other ancestry placebo-controlled cases
Region17q25.1
Chromosome idchr17
Chromosome position73531941
Reported geneSDK2
Mapped geneSDK2
Upstream gene id
Downstream gene id
SNP gene ids54549
Upstream gene distance
Downstream gene distance
SNP risk allelers1872085-?
SNPsrs1872085
Merged
SNP id current1872085
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.000002
Pvalue mlog5.69897000433601
P value text(Recessive model)
Or beta0.69
%95 Ciunit increase
PlatformIllumina [542562]
CNVN
Mapped traitFEV change measurement, response to zileuton, asthma
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005921, http://www.ebi.ac.uk/efo/EFO_0007676, http://www.ebi.ac.uk/efo/EFO_0000270
Study accessionGCST002951