SNP Detail For rs1867982
1.Mapping Information
Human SNP ID rs1867982
Human chromosome chr10
Human SNP position 71767290
Pig chromosome chr14
Pig SNP position 80578559
2.Annotation Information
PubMed ID22424883
JournalJ Allergy Clin Immunol
Linkwww.ncbi.nlm.nih.gov/pubmed/22424883
StudyGenome-wide association study of lung function decline in adults with and without asthma.
Disease/TraitPulmonary function decline
Initial sample1,441 European ancestry asthma cases, 2,677 European ancestry controls
Replication sample1,160 European ancestry asthma cases, 10,858 European ancestry controls
Region10q22.1
Chromosome idchr10
Chromosome position71767290
Reported geneintergenic
Mapped geneCDH23, C10orf54
Upstream gene id
Downstream gene id
SNP gene ids64072, 64115
Upstream gene distance
Downstream gene distance
SNP risk allelers1867982-?
SNPsrs1867982
Merged0
SNP id current1867982
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.000006
Pvalue mlog5.22184874961635
P value text(FEV1/FVC decline in non-asthmatics)
Or beta0.2018
%95 Ci[0.11-0.29] unit increase
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitFEV/FEC ratio
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST001444
PubMed ID21685187
JournalThorax
Linkwww.ncbi.nlm.nih.gov/pubmed/21685187
StudyGenome-wide association study of smoking behaviours in patients with COPD.
Disease/TraitAge at smoking initiation in chronic obstructive pulmonary disease
Initial sample3,397 European ancestry cases
Replication sampleNA
Region10q22.1
Chromosome idchr10
Chromosome position71767290
Reported geneCDH23
Mapped geneCDH23, C10orf54
Upstream gene id
Downstream gene id
SNP gene ids64072, 64115
Upstream gene distance
Downstream gene distance
SNP risk allelers1867982-A
SNPsrs1867982
Merged0
SNP id current1867982
Contextintron_variant
Intergenic0
Allele frequency0.11
P value0.000009
Pvalue mlog5.04575749056067
P value text
Or beta0.058
%95 Ciunit increase
PlatformIllumina [~ 6300000] (imputed)
CNVN
Mapped traitchronic obstructive pulmonary disease, smoking initiation
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000341, http://www.ebi.ac.uk/efo/EFO_0005670
Study accessionGCST001113