Human SNP ID | rs1837253 |
---|---|
Human chromosome | chr5 |
Human SNP position | 111066174 |
Pig chromosome | chr2 |
Pig SNP position | 120313819 |
PubMed ID | 21804549 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21804549 |
Study | Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. |
Disease/Trait | Asthma |
Initial sample | 2,088 European ancestry cases, 1,612 African American and African Caribbean cases, 1,688 Hispanic cases |
Replication sample | 2,727 European ancestry cases, 2,147 African American and African Caribbean cases, 2,299 Hispanic cases |
Region | 5q22.1 |
Chromosome id | chr5 |
Chromosome position | 111066174 |
Reported gene | TSLP |
Mapped gene | LOC105379121 - TSLP |
Upstream gene id | 105379121 |
Downstream gene id | 85480 |
SNP gene ids | |
Upstream gene distance | 51554 |
Downstream gene distance | 3906 |
SNP risk allele | rs1837253-? |
SNPs | rs1837253 |
Merged | 0 |
SNP id current | 1837253 |
Context | upstream_gene_variant |
Intergenic | 1 |
Allele frequency | NR |
P value | 0.00000000000001 |
Pvalue mlog | 14 |
P value text | |
Or beta | |
%95 Ci | |
Platform | Affymetrix, Illumina [> 2000000] (imputed) |
CNV | N |
Mapped trait | asthma |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000270 |
Study accession | GCST001182 |
PubMed ID | 21804548 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21804548 |
Study | Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population. |
Disease/Trait | Asthma |
Initial sample | 1,532 Japanese ancestry cases, 3,304 Japanese ancestry controls |
Replication sample | 5,639 Japanese ancestry cases, 24,608 Japanese ancestry controls |
Region | 5q22.1 |
Chromosome id | chr5 |
Chromosome position | 111066174 |
Reported gene | TSLP |
Mapped gene | LOC105379121 - TSLP |
Upstream gene id | 105379121 |
Downstream gene id | 85480 |
SNP gene ids | |
Upstream gene distance | 51554 |
Downstream gene distance | 3906 |
SNP risk allele | rs1837253-C |
SNPs | rs1837253 |
Merged | 0 |
SNP id current | 1837253 |
Context | upstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.35 |
P value | 0.0000000000000001 |
Pvalue mlog | 16 |
P value text | |
Or beta | 1.17 |
%95 Ci | [1.13-1.22] |
Platform | Illumina [458847] |
CNV | N |
Mapped trait | asthma |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000270 |
Study accession | GCST001183 |
PubMed ID | 24388013 |
Journal | J Allergy Clin Immunol |
Link | www.ncbi.nlm.nih.gov/pubmed/24388013 |
Study | Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype. |
Disease/Trait | Asthma and hay fever |
Initial sample | 6,685 European ancestry cases, 14,091 European ancestry controls |
Replication sample | 878 European ancestry cases, 2,455 European ancestry controls |
Region | 5q22.1 |
Chromosome id | chr5 |
Chromosome position | 111066174 |
Reported gene | TSLP |
Mapped gene | LOC105379121 - TSLP |
Upstream gene id | 105379121 |
Downstream gene id | 85480 |
SNP gene ids | |
Upstream gene distance | 51554 |
Downstream gene distance | 3906 |
SNP risk allele | rs1837253-C |
SNPs | rs1837253 |
Merged | 0 |
SNP id current | 1837253 |
Context | upstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.71 |
P value | 0.000000001 |
Pvalue mlog | 9 |
P value text | |
Or beta | 1.17 |
%95 Ci | [1.12-1.24] |
Platform | Illumina [up to 4972397] (imputed) |
CNV | N |
Mapped trait | seasonal allergic rhinitis, asthma |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003956, http://www.ebi.ac.uk/efo/EFO_0000270 |
Study accession | GCST002322 |