SNP Detail For rs183266
1.Mapping Information
Human SNP ID rs183266
Human chromosome chr14
Human SNP position 77031632
Pig chromosome chr7
Pig SNP position 106156998
2.Annotation Information
PubMed ID22379998
JournalPharmacogenomics
Linkwww.ncbi.nlm.nih.gov/pubmed/22379998
StudyGenome-wide mapping for clinically relevant predictors of lamotrigine- and phenytoin-induced hypersensitivity reactions.
Disease/TraitAdverse response to lamotrigine and phenytoin
Initial sample34 European ancestry lamotrigine-induced hypersensitivity cases, 42 European ancestry phenytoin-induced hypersensitivity cases, 1,296 European ancestry controls
Replication sampleNA
Region14q24.3
Chromosome idchr14
Chromosome position77031632
Reported geneIRF2BPL
Mapped geneIRF2BPL - LOC105370579
Upstream gene id64207
Downstream gene id105370579
SNP gene ids
Upstream gene distance2933
Downstream gene distance736
SNP risk allelers183266-?
SNPsrs183266
Merged0
SNP id current183266
Contextupstream_gene_variant
Intergenic1
Allele frequencyNR
P value0.000005
Pvalue mlog5.30102999566398
P value text(LTG)
Or beta
%95 Ci
PlatformIllumina [NR]
CNVN
Mapped traitresponse to anticonvulsant
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0036277
Study accessionGCST001431