SNP Detail For rs182554582
1.Mapping Information
Human SNP ID rs182554582
Human chromosome chr10
Human SNP position 86435202
Pig chromosome chr14
Pig SNP position 94746633
2.Annotation Information
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region10q23.2
Chromosome idchr10
Chromosome position86435202
Reported geneIntergenic
Mapped geneGRID1 - WAPAL
Upstream gene id2894
Downstream gene id23063
SNP gene ids
Upstream gene distance68709
Downstream gene distance54
SNP risk allelers182554582-A
SNPsrs182554582
Merged0
SNP id current182554582
Contextdownstream_gene_variant
Intergenic1
Allele frequency0.999
P value0.0000005
Pvalue mlog6.30102999566398
P value text(AA)
Or beta2.216
%95 CiNR unit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitforced expiratory volume, response to bronchodilator
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366
Study accessionGCST003262
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region10q23.2
Chromosome idchr10
Chromosome position86435202
Reported geneIntergenic
Mapped geneGRID1 - WAPAL
Upstream gene id2894
Downstream gene id23063
SNP gene ids
Upstream gene distance68709
Downstream gene distance54
SNP risk allelers182554582-A
SNPsrs182554582
Merged0
SNP id current182554582
Contextdownstream_gene_variant
Intergenic1
Allele frequency0.999
P value0.0000008
Pvalue mlog6.09691001300805
P value text(AA)
Or beta0.433
%95 Ciunit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003264