SNP Detail For rs181167431
1.Mapping Information
Human SNP ID rs181167431
Human chromosome chr16
Human SNP position 74045127
Pig chromosome chr6
Pig SNP position 15856754
2.Annotation Information
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region16q22.3
Chromosome idchr16
Chromosome position74045127
Reported geneIntergenic
Mapped geneLOC107984856 - LOC101928035
Upstream gene id107984856
Downstream gene id101928035
SNP gene ids
Upstream gene distance38355
Downstream gene distance147265
SNP risk allelers181167431-A
SNPsrs181167431
Merged0
SNP id current181167431
Contextintergenic_variant
Intergenic1
Allele frequency1
P value0.000001
Pvalue mlog6
P value text(AA)
Or beta2.522
%95 CiNR unit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitforced expiratory volume, response to bronchodilator
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366
Study accessionGCST003262
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region16q22.3
Chromosome idchr16
Chromosome position74045127
Reported geneIntergenic
Mapped geneLOC107984856 - LOC101928035
Upstream gene id107984856
Downstream gene id101928035
SNP gene ids
Upstream gene distance38355
Downstream gene distance147265
SNP risk allelers181167431-A
SNPsrs181167431
Merged0
SNP id current181167431
Contextintergenic_variant
Intergenic1
Allele frequency1
P value0.0000001
Pvalue mlog7
P value text(AA)
Or beta0.541
%95 Ciunit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003264