SNP Detail For rs1809529
1.Mapping Information
Human SNP ID rs1809529
Human chromosome chr3
Human SNP position 10835926
Pig chromosome chr13
Pig SNP position 74220530
2.Annotation Information
PubMed ID22491018
JournalPharmacogenomics J
Linkwww.ncbi.nlm.nih.gov/pubmed/22491018
StudyGenome-wide association analysis implicates the involvement of eight loci with response to tocilizumab for the treatment of rheumatoid arthritis.
Disease/TraitResponse to tocilizumab in rheumatoid arthritis
Initial sample1,157 European and other ancestry rheumatoid arthritis cases
Replication sample526 European and other ancestry rheumatoid arthritis cases
Region3p25.3
Chromosome idchr3
Chromosome position10835926
Reported geneSLC6A11
Mapped geneSLC6A11
Upstream gene id
Downstream gene id
SNP gene ids6538
Upstream gene distance
Downstream gene distance
SNP risk allelers1809529-?
SNPsrs1809529
Merged0
SNP id current1809529
Contextintron_variant
Intergenic0
Allele frequency0.34
P value0.0000003
Pvalue mlog6.52287874528033
P value text(CHAQ, RF-)
Or beta0.28
%95 Ci[NR] unit increase
PlatformIllumina [534053]
CNVN
Mapped traitrheumatoid arthritis, response to drug
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000685, http://purl.obolibrary.org/obo/GO_0042493
Study accessionGCST001476