Human SNP ID | rs1805081 |
---|---|
Human chromosome | chr18 |
Human SNP position | 23560468 |
Pig chromosome | chr6 |
Pig SNP position | 101028838 |
PubMed ID | 19151714 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/19151714 |
Study | Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations. |
Disease/Trait | Obesity |
Initial sample | 695 European ancestry adult cases, 731 European ancestry adult controls, 685 European ancestry child cases, 685 European ancestry child controls |
Replication sample | 1,171 European ancestry adult cases, 1,114 European ancestry adult controls, 4,417 European ancestry adults, 896 European ancestry child cases, 1,297 European ancestry child and young adult controls, 5,291 European ancestry children |
Region | 18q11.2 |
Chromosome id | chr18 |
Chromosome position | 23560468 |
Reported gene | NPC1 |
Mapped gene | NPC1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 4864 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs1805081-A |
SNPs | rs1805081 |
Merged | 0 |
SNP id current | 1805081 |
Context | missense_variant |
Intergenic | 0 |
Allele frequency | 0.56 |
P value | 0.0000003 |
Pvalue mlog | 6.52287874528033 |
P value text | |
Or beta | |
%95 Ci | |
Platform | Illumina [308846] |
CNV | N |
Mapped trait | obesity |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0001073 |
Study accession | GCST000317 |
PubMed ID | 19151714 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/19151714 |
Study | Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations. |
Disease/Trait | Obesity |
Initial sample | 695 European ancestry adult cases, 731 European ancestry adult controls, 685 European ancestry child cases, 685 European ancestry child controls |
Replication sample | 1,171 European ancestry adult cases, 1,114 European ancestry adult controls, 4,417 European ancestry adults, 896 European ancestry child cases, 1,297 European ancestry child and young adult controls, 5,291 European ancestry children |
Region | 18q11.2 |
Chromosome id | chr18 |
Chromosome position | 23560468 |
Reported gene | NPC1 |
Mapped gene | NPC1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 4864 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs1805081-A |
SNPs | rs1805081 |
Merged | 0 |
SNP id current | 1805081 |
Context | missense_variant |
Intergenic | 0 |
Allele frequency | 0.6 |
P value | 0.00000008 |
Pvalue mlog | 7.09691001300805 |
P value text | (adults) |
Or beta | 1.41 |
%95 Ci | [1.19-1.61] |
Platform | Illumina [308846] |
CNV | N |
Mapped trait | obesity |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0001073 |
Study accession | GCST000317 |