Human SNP ID | rs1800789 |
---|---|
Human chromosome | chr4 |
Human SNP position | 154561591 |
Pig chromosome | chr8 |
Pig SNP position | 78963477 |
PubMed ID | 20031576 |
---|---|
Journal | Circ Cardiovasc Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/20031576 |
Study | Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts. |
Disease/Trait | Fibrinogen |
Initial sample | 22,096 European ancestry individuals |
Replication sample | 17,686 European ancestry female individuals |
Region | 4q31.3 |
Chromosome id | chr4 |
Chromosome position | 154561591 |
Reported gene | FGB |
Mapped gene | PLRG1 - FGB |
Upstream gene id | 5356 |
Downstream gene id | 2244 |
SNP gene ids | |
Upstream gene distance | 11158 |
Downstream gene distance | 1389 |
SNP risk allele | rs1800789-A |
SNPs | rs1800789 |
Merged | 0 |
SNP id current | 1800789 |
Context | upstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.22 |
P value | 2E-30 |
Pvalue mlog | 29.698970004336 |
P value text | |
Or beta | 0.09 |
%95 Ci | [0.07-0.11] g/L increase |
Platform | Affymetrix, Illumina [~ 2661766] (imputed) |
CNV | N |
Mapped trait | fibrinogen measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004623 |
Study accession | GCST000366 |
PubMed ID | 23969696 |
Journal | Circulation |
Link | www.ncbi.nlm.nih.gov/pubmed/23969696 |
Study | Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. |
Disease/Trait | Fibrinogen |
Initial sample | 91,323 European ancestry individuals |
Replication sample | 8,423 African American individuals, 1,447 Hispanic individuals |
Region | 4q31.3 |
Chromosome id | chr4 |
Chromosome position | 154561591 |
Reported gene | FGB |
Mapped gene | PLRG1 - FGB |
Upstream gene id | 5356 |
Downstream gene id | 2244 |
SNP gene ids | |
Upstream gene distance | 11158 |
Downstream gene distance | 1389 |
SNP risk allele | rs1800789-A |
SNPs | rs1800789 |
Merged | 0 |
SNP id current | 1800789 |
Context | upstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.21 |
P value | 2E-127 |
Pvalue mlog | 126.698970004336 |
P value text | |
Or beta | 0.031 |
%95 Ci | [0.029-0.033] unit increase |
Platform | Affymetrix, Illumina [2515567] (imputed) |
CNV | N |
Mapped trait | fibrinogen measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004623 |
Study accession | GCST002147 |