SNP Detail For rs1800469
1.Mapping Information
Human SNP ID rs1800469
Human chromosome chr19
Human SNP position 41354391
Pig chromosome chr6
Pig SNP position 45142538
2.Annotation Information
PubMed ID24836286
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/24836286
StudyLarge-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk.
Disease/TraitColorectal cancer
Initial sample2,098 East Asian ancestry cases, 6,172 East Asian ancestry controls
Replication sample12,865 East Asian ancestry cases, 25,773 East Asian ancestry controls, up to 16,984 European ancestry cases, up to 18,262 European ancestry controls
Region19q13.2
Chromosome idchr19
Chromosome position41354391
Reported geneTGFB1, B9D2
Mapped geneTGFB1 - B9D2
Upstream gene id7040
Downstream gene id80776
SNP gene ids
Upstream gene distance458
Downstream gene distance26
SNP risk allelers1800469-G
SNPsrs1800469
Merged0
SNP id current1800469
Contextintron_variant
Intergenic1
Allele frequency0.48
P value0.00000001
Pvalue mlog8
P value text(East Asian)
Or beta1.09
%95 Ci[1.06-1.12]
PlatformAffymetrix, Illumina [2400000] (imputed)
CNVN
Mapped traitcolorectal cancer
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005842
Study accessionGCST002454